Published online Sep 26, 2020. doi: 10.4252/wjsc.v12.i9.1001
Peer-review started: February 28, 2020
First decision: July 5, 2020
Revised: July 28, 2020
Accepted: September 1, 2020
Article in press: September 1, 2020
Published online: September 26, 2020
Core Tip: Oropharyngeal dysphagia, despite its widespread prevalence, is a difficult condition to treat, particularly in those who have undergone irradiation or resection in the head and neck. This challenge stems from the lack of native functional tissue upon which current therapies such as physical rehabilitation rely. There have been several studies examining the use of stem cell therapy as a potential new treatment option for these patients. Our objective is to review and consolidate the current literature regarding this topic and discuss the recent advancements, challenges, and future directions for research in this field.