CR6-interacting factor-1 contributes to osteoclastogenesis by inducing receptor activator of nuclear factor κB ligand after radiation
Li-Xin Xiang, Qian Ran, Li Chen, Yang Xiang, Feng-Jie Li, Xiao-Mei Zhang, Yan-Ni Xiao, Zhong-Jun Li, Laboratory Medicine Center, Department of Blood Transfusion, Lab of Radiation Biology, The Second Affiliated Hospital, Third Military Medical University, Chongqing, 400037, China
Qian Ran, Yang Xiang, Jiang F Zhong, Department of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, United States
Ling-Yun Zou, Bioinformatics Center, College of Basic Medical Sciences, Third Military Medical University, Chongqing 400038, China
Shengwen Calvin Li, CHOC Children’s Research Institute, Children’s Hospital of Orange County, University of California, Irvine, CA 92868, United States
Author contributions: Li ZJ and Xiang LX conceived the study; Xiang LX designed and performed most experiments and data analysis; Chen L, Xiang Y, Li FJ, Zhang XM, Xiao YN, Zou LY, Zhong JF, Li SC, and Ran Q assisted with experiments and data analysis; Xiang LX wrote and edited the manuscript; Li ZJ supervised the study; all authors read and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 81502754 and No. 31571352; and Interdisciplinary and International Cooperation Projects of The Second Affiliated Hospital, Third Military Medical University, No. 2016YXKJC0.
Institutional review board statement: Not applicable.
Institutional animal care and use committee statement: All animal studies performed were approved by the Laboratory Animal Welfare and Ethics Committee Of the Third Military Medical University.
Conflict-of-interest statement: The authors report no conflicts of interest in this work.
Data sharing statement: No additional data are available.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zhong-Jun Li, MD, Professor, Chief, Laboratory Medicine Center, Department of Blood Transfusion, Lab of Radiation Biology, The Second Affiliated Hospital, Third Military Medical University, Xinqiao Road, Chongqing 400037, China. firstname.lastname@example.org
Received: January 23, 2020
Peer-review started: January 23, 2020
First decision: February 19, 2020
Revised: March 9, 2020
Accepted: March 15, 2020
Article in press: March 15, 2020
Published online: March 26, 2020