临床研究
Copyright ©The Author(s) 2020.
世界华人消化杂志. 2020-10-08; 28(19): 964-971
在线出版 2020-10-08. doi: 10.11569/wcjd.v28.i19.964
表1 胃癌患者死亡相关因素的单因素生存分析
变量总体死亡人数(%)χ2P
年龄(岁)144.6430.000
≤4027368 (38.4)
41-50742169 (31.6)
51-601457396 (37.8)
61-701756637 (45.9)
>70794388 (60.0)
性别0.8930.345
38881305 (44.1)
1134353 (42.3)
吸烟0.6350.425
2151722 (44.8)
2844917 (42.4)
饮酒0.1190.730
1047343 (42.7)
39431294 (43.6)
T分期335.3150.000
T169153 (10.8)
T252080 (21.3)
T3592176 (42.0)
T42343949 (53.2)
N分期299.0750.000
N01553223 (20.2)
N1914278 (43.2)
N2776297 (50.1)
N3588283 (57.8)
M分期367.3400.000
M03657968 (36.1)
M1548309(71.7)
肿瘤大小(cm)180.4350.000
<51817325 (23.4)
≥51789612(49.9)
肿瘤位置27.2290.000
上部1038409 (47.7)
中部1010294 (37.9)
下部2044548 (37.5)
淋巴结转移233.6710.000
2023738 (48.6)
1433198 (19.7)
分化程度36.5080.000
37581 (28.1)
1359416 (38.8)
2279768 (47.4)
混合型179105 (33.5)
Borrmann's分型66.4300.000
526135 (31.7)
1299273 (35.0)
1222403 (43.3)
1008424 (50.2)
病理分型6.9150.075
腺癌40391270 (42.5)
粘液腺癌9136 (50.7)
印戒细胞癌15550 (39.7)
其他11432 (33.3)
临床分期524.0260.000
70672 (21.5)
638152 (27.2)
1248515 (47.3)
548311 (68.8)
手术577.3660.000
3390799 (32.0)
1631859 (66.1)
化疗0.3700.543
1295435 (39.7)
1617579 (41.7)
放疗3.2320.072
12458 (52.3)
2398835 (41.1)
治疗方式151.4450.000
根治性切除术2397526 (32.0)
放化疗277147 (61.9)
术后放化疗986271 (32.1)
表2 5022例胃癌患者预后生存相关危险因素的多因素生存分析
变量βSEWaldPHR (95%CI)
年龄
41-501.000
≤400.15402420.4070.5321.167 (0.727, 1.873)
51-600.3400.1554.7800.0291.405 (1.036, 1.9905)
61-700.4980.15310.5790.0011.645 (1.219, 2.221)
>700.7860.17819.5300.0002.196 (1.549, 3.112)
T分期
T11.000
T20.6510.2675.9480.0151.918 (1.136, 3.237)
T31.0920.25817.8940.0002.979 (1.797, 4.941)
T41.2780.24427.3470.0003.589 (2.223, 5.794)
N分期
N01.000
N10.4780.1965.9390.0151.613 (1.098, 2.369)
N20.6180.19410.1620.0011.855 (1.269, 2.712)
N30.9230.20320.7460.0002.518 (1.692, 3.747)
M分期
M01.000
M10.6610.2258.6630.0031.937 (1.247, 3.008)
肿瘤大小
<5 cm1.000
≥5 cm0.3530.09513.8560.0001.423 (1.182, 1.713)
肿瘤位置
上部1.000
中部-0.2690.1274.4970.0340.764 (0.596, 0.980)
下部-0.2190.1064.2770.0390.803 (0.653, 0.989)
淋巴结转移
1.000
0.0950.1720.3060.5801.100 (0.785, 1.539)
分化程度
1.000
-0.2210.0965.2280.0220.802 (0.664, 0.969)
-0.4670.2025.3140.0210.627 (0.422, 0.933)
Borrmann分型
1.000
0.1690.1521.2350.2671.184 (0.879, 1.595)
0.2220.1482.2420.1341.248 (0.934, 1.669)
-0.1320/1620.6650.4150.876 (0.638, 1.204)
治疗方式
1.000
放化疗0.3800.7440.2610.6101.462 (0.340, 6.283)
术后放化疗-0.9930.17333.0780.0000.371 (0.264, 0.520)
根治性切除术-0.6290.16614.2880.0000.533 (0.385, 0.739)

引文著录: 曹娟, 王冠华, 伍静, 赵丹, 王文凡, 张晓旭, 阮继刚, 杨文君. 宁夏胃癌病例流行现状及预后5022例分析. 世界华人消化杂志 2020; 28(19): 964-971