Telomerase activity and cell apoptosis in colon cancer cell by human telomerase reverse transcriptase gene antisense oligodeoxynucleotide

Table 1 Effect of telomerase activity in SW480 cells by ODNs (^-x±s)

Groups	Active duration
	24 h	48 h	72 h	96 h	120 h
As-ODN 10 μmol/L	0.648 ± 0.057	0.324 ± 0.029	0.283 ± 0.072	0.189 ± 0.093	0.172 ± 0.114
S-ODN 10 μmol/L	1.082 ± 0.249	1.272 ± 0.372	1.204 ± 0.190	0.902 ± 0.193	0.909 ± 0.146
Positive control	1.336 ± 0.231	1.376 ± 0.238	1.354 ± 0.186	1.298 ± 0.172	1.246 ± 0.169
Negative control	0.339 ± 0.181	0.312 ± 0.139	0.283 ± 0.086	0.072 ± 0.039	0.057 ± 0.028

Table 2 Effect of ODNs on induction of SW480 cells apoptosis (^-x±s)

Groups	Active duration
	48 h	72 h	96 h
As-ODN 10 μmol/L	4.82 ± 0.39	8.76 ± 0.14	9.25 ± 0.37
S-ODN 10 μmol/L	2.08 ± 0.38	2.96 ± 0.47	2.19 ± 0.29
hTERT blank	1.47 ± 0.14	1.49 ± 0.21	1.44 ± 0.19