Colorectal Cancer
Copyright ©The Author(s) 2003.
World J Gastroenterol. May 15, 2003; 9(5): 956-960
Published online May 15, 2003. doi: 10.3748/wjg.v9.i5.956
Table 1 Odds ratios for colon cancer according to the geno-types of hOGG1 Ser326Cys polymorphism
Number (%)
OR (95%CI)P for trend
ControlsCases
Ser/Ser52 (21.1)24 (19.2)1.00
Ser/Cys131 (53.0)66 (52.8)1.09 (0.60-2.00)P = 0.871
Cys/Cys64 (25.9)35 (28.0)1.18 (0.60-2.35)
Total247 (100)125 (100)
Table 2 ORs for colon cancer according to individual habits and familial history of colon cancer with reference to the hOGG1 Ser326Cys polymorphism
Total
hOGG1 Ser326Cys polymorphi sm
Ca/CoOR95%CISer/Ser + ser/Cys
Cys/Cys
Ca/CoOR95%CICa/CoOR95%CI
Smoking
No44/1061-35/751-9/311-
Yes81/1411.530.94-2.5255/1081.080.62-1.8426/332.751.07-7.53
Drinking
< 2times/wk73/1611-53/1221-20/391-
> 2times/wk52/861.370.87-2.3237/611.490.87-2.7715/251.210.49-3.02
Meat
< 2time/week66/1591-52/112-14/471-
> 2time/week59/881.721.12-2.7638/711.270.73-2.1321/174.311.64-11.48
Vegetable intake
Low50/891-36/701-14/191-
High75/1580.80.49-1.3154/1130.90.46-1.6721/451.550.50-4.19
Soybean product
< 3/wk55/115137/871-18/281-
> 3/wk70/1321.110.70-1.7553/961.30.76-2.2317/360.730.30-1.82
Activity
< 4 hs/wk61/1041-43/75-18/291-
> 4hs/wk64/1430.760.48-1.2047/1080.760.44-1.3017/350.780.32-1.94
Familial history of colon cancer
No84/1851-62/138-22/471-
Yes41/621.460.80-2.4028/451.380.76-2.5113/171.630.62-4.32