Glucose intolerance in Chinese patients with chronic hepatitis C

Table 1 Comparisons of demographic data between chronic hepatitis C patients with glucose intolerance* and normal fasting glucose

	Patients with glucose intolerance (n = 125)	Patients with normal fasting glucose (n = 234)	P value
Age	61.1 ± 11.2	56.6 ± 13.6	0.001
Sex (male:female)	47:78	99:135	0.452
Body mass index (kg/m2)	24.5 ± 3.7	23.7 ± 3.2	0.024
Family history of DM (+:-)	37:88	30:204	< 0.001
Obesity (+:-)	38:87	49:185	0.046
Liver cirrhosis (+:-)	28:97	47:187	0.706
Previous interferon treatment (+:-)	51:74	66:168	0.021

Denotes: Data were expressed as mean ± S.D. * Patients with glucose intolerance included patients with diabetes mellitus and impaired fasting glucose by the diagnostic criteria of the American Diabetic Association.

Table 2 Significant predictive variables of glucose intolerance in chronic hepatitis C patients using stepwise multivariate logistic regression analysis

	Coefficient	Odds ratio	95%CI	P value
Age 57 years	1.251	3.50	2.06-5.92	< 0.001
Diabetic family history	1.289	3.64	2.00-6.57	< 0.001
Obesity	0.576	1.78	1.05-3.03	0.034
Previous interferon treatment	0.803	2.23	1.34-3.72	0.002

Denotes: CI: confidence interval.