Liang W, Wang H, Sun TM, Yao WQ, Chen LL, Jin Y, Li CL, Meng FJ. Application of autologous tumor cell vaccine and NDV vaccine in treatment of tumors of digestive traet. World J Gastroenterol 2003; 9(3): 495-498 [PMID: 12632504 DOI: 10.3748/wjg.v9.i3.495]
Corresponding Author of This Article
Wen-Qing Yao, Liaoning Provincal Tumor Research Institute, 44 xiaoheYan Road, Dadong District, Shenyang 110042, Liaoning Province, China. yaowenq@mail.sy.ln.cn Telephone: +86-24-24324202
Article-Type of This Article
Colorectal Cancer
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Table 6 Comparison of fve-year survival rate, survival period of resected colorectal cancer patients in vaccination group with positive and negative DTH reaction
Table 7 The remission rate of late cancer of digestive tract carcinoma treated with NDV vaccine
Types of disease
n
CR(%)
PR(%)
SD(%)
PD(%)
CR+PR(%)
Colorectal cancer
13
1
3
8
0
4
Stomach cancer
6
0
0
5
0
0
Liver caner
4
0
2
1
0
2
Pancreatic head cancer
1
0
0
1
1
0
Gall bladder cancer
1
0
0
1
0
0
Total
25
1(4.00%)
5(20.00%)
16(64.00%)
1(4.00%)
6(24.00%)
Table 8 Comparison of treatment courses and therapeutic ef-fect of colorectal cancer patients with NDV immunotherapy
Group
n
CR
PR
SD
PD
CR+PR
1 Course
6
0
0
5
1
0
> 2 Courses
7
1
3
3
0
4
Table 9 Immunobgice function prior to and after NDV vaccination therapy
Item
n
Before therapy(-x ± s)
After therapy (-x ± s)
P
NK
10
24.65 ± 7.21
36.58 ± 11.87
< 0.05
CD3+
10
67.15 ± 2.43
71.12 ± 2.86
< 0.01
CD4+
10
38.23 ± 3.01
41.62 ± 2.71
< 0.01
CD8+
10
30.55 ± 1.21
29.84 ± 2.43
> 0.05
CD4+/CD8+
10
1.23 ± 0.12
1.41 ± 0.13
< 0.05
Citation: Liang W, Wang H, Sun TM, Yao WQ, Chen LL, Jin Y, Li CL, Meng FJ. Application of autologous tumor cell vaccine and NDV vaccine in treatment of tumors of digestive traet. World J Gastroenterol 2003; 9(3): 495-498