Effects of time interval for hemofiltration on the prognosis of severe acute pancreatitis

Table 1 Parameters of hemofiltration in two groups

Indices	Group 1 ( ≤ 5 h)	Group 2 (5-20 h)	P values
Number	20	16
Age (yr)	52.4 ± 14.2	45.1 ± 9.2	> 0.05
APACHE before HF	13.9 ± 3.8	12.1 ± 4.2	> 0.05
Beginning time (h)	45.9 ± 21.2	37.4 ± 12.5	> 0.05
Rate of substitute (mL/h)	2700 ± 500	2880 ± 300	> 0.05
Blood flow (mL/min)	200~250	250~360	> 0.05
Rate of ultrafiltrate (mL/h)	342.5 ± 251	240 ± 72	> 0.05
Time interval (h)	3.81 ± 1.3	9.38 ± 2.9	< 0.01
Colloid volume (mL)	700 ± 258.2	1500 ± 852.9	< 0.01
The amount of haparin (IU)	7700 ± 2341.1	12000 ± 6000	< 0.01
Substitute volume (L)	9.5 ± 3.2	35.1 ± 16.5	< 0.01
Ultrafiltrate Volume (mL)	1040 ± 520	2400 ± 700	< 0.01
Filters	1.44 ± 0.73	2.75 ± 1.4	< 0.05

Table 2 Indices of prognosis of severe acute pancreatitis

Indices	Group1 ( ≤ 5 h)	Group 2 (5-20 h)	P values
Number	20	16
Conservative curing rate (%)	90% (18/20)	56.3% (9/16)	< 0.05
Survival rate (%)	95% (19/20)	81.3% (13/16)	< 0.25
Cost (× 104 yuan)	5.66 ± 5.64	13.7 ± 10.5	< 0.05
Hospital stay (d)	44.3 ± 17.3	55.2 ± 29.5	< 0.2