Effects of glycine on plasma and liver tissue changes of TNF-α, ET-1 and nitric oxide contents in rats with obstructive jaundice

Table 1 Plasma levels of bilirubin, endotoxin, TNF-α, ET-1 and NO₂^-/NO₃^- in different groups of rats (x^-±s, n = 30)

Group	Bilirubin (μmol/L)	Endotoxin (Eu/mL)	TNF-α (pg/mL)	ET-1 (pg/mL)	NO2-/NO3- (μmol/L)
A	5.80 ± 1.65	5.98 ± 1.00	61.37 ± 3.08	88.79 ± 7.56	5.51 ± 0.44
B	45.45 ± 6.69a	11.65 ± 1.57a	352.52 ± 20.65a	183.24 ± 34.01a	12.06 ± 0.62a
C	43.18 ± 6.53a	11.27 ± 1.30a	158.63 ± 7.07ab	120.68 ± 10.99ab	8.55 ± 0.40ab

^aP < 0.01 vs group A,

^bP < 0.01 vs group B.

Table 2 Levels of TNF-α, ET-1 and NO₂^-/NO₃^- in liver tissues of different groups of rats (x^-±s)

Group	Samples	TNF-α (pg/mL)	ET-1 (pg/mL)	NO2-/NO3- (μmol/L)
A	10	43.51 ± 2.58	43.18 ± 4.47	2.15 ± 0.18
B	10	298.46 ± 18.74a	124.56 ± 11.67a	10.53 ± 0.87a
C	10	113.45 ± 6.67ab	81.49 ± 7.39ab	7.23 ± 0.34ab

^aP < 0.01 vs group A,

^bP < 0.01 vs group B.