Effect of resveratrol on cell cycle proteins in murine transplantable liver cancer

Table 1 The suppressing effect of resveratrol on murine trans-planted liver tissue

	Dose (mg/kg)	No. of mice (begin/end)	Tumour size (mm3, x-±s)	GIR (%)
Control group	0	10/9	134 ± 40
Resveratrol	5.0	10/10	105 ± 14a	21.6
	10.0	10/10	85 ± 22b	36.3
	15.0	10/9	68 ± 17b	49.3

^aP > 0.05,

^bP < 0.01, vs control.

Table 2 Effect of resveratrol on the expression of cyclin D1 in murine liver tumor and adjacent noncancerous liver tissues

	No. of mice	Cyclin D1			Positive rate (%)
		-	+	++	(+, ++)
Noncancerous tissues	9	9	0	0	0
Control group	9	3	2	4	66.7a
Therapeutic group	10	4	3	3	60.0b

^aP < 0.01, vs noncancerous tissues;

^bP > 0.05, vs control.

Table 3 Effect of resveratrol on the expression of cyclin B1 in murine liver tumor and adjacent noncancerous liver tissues

	No. of mice	CyclinB1			Positive rate (%)
		-	+	++	(+,++)
Noncancerous tissues	9	7	1	1	22.2
Control group	9	2	2	5	77.8a
Therapeutic group	10	7	2	1	30.0b

^aP < 0.05, vs noncancerous tissues;

^bP < 0.05, vs control.

Table 4 Effect of resveratrol on the expression of p34cdc2 in murine liver tumor and adjacent noncancerous liver tissues

	No. of mice	p34cdc2			Positive rate (%)
		-	+	++	(+,++)
Noncancerous tissues	9	7	2	0	22.2
Control group	9	1	3	5	88.9a
Therapeutic group	10	6	3	1	40.0b

^aP < 0.01, vs noncancerous tissues;

^bP < 0.05, vs control.