Gastric Cancer
Copyright ©The Author(s) 2002.
World J Gastroenterol. Dec 15, 2002; 8(6): 999-1004
Published online Dec 15, 2002. doi: 10.3748/wjg.v8.i6.999
Table 1 Cell cycle analysis of SGC-7901 cells induced by c9, t11-CLA at 24 h and 48 h (mean ± SD, n = 4)
c9,t11-CLA(μm)Apoptosis
G0/G1
G2/M
S
24 h48 h24 h48 h24 h48 h24 h48 h
00.55 ± 0.090.69 ± 0.2153.13 ± 3.4458.57 ± 0.9011.13 ± 2.7512.64 ± 1.1835.74 ± 2.0428.80 ± 0.89
251.27 ± 0.733.89 ± 2.1253.00 ± 8.3556.81 ± 1.0915.55 ± 1.1115.95 ± 0.3631.40 ± 9.2326.52 ± 1.46
504.12 ± 0.55a8.18 ± 1.55b56.58 ± 0.8756.32 ± 0.7814.55 ± 3.4515.17 ± 0.6128.87 ± 3.3228.51 ± 1.32
1007.95 ± 0.31b12.33 ± 1.53b58.35 ± 2.4461.18 ± 4.9413.12 ± 1.5014.49 ± 3.1028.52 ± 0.9625.08 ± 2.85
20012.79 ± 3.12b14.75 ± 5.97b60.67 ± 4.28a63.82 ± 7.84a12.95 ± 4.4813.35 ± 3.9126.38 ± 0.92b22.82 ± 4.63b
Table 2 Positive rates of bcl-2, Fas and c-myc on SGC-7901 cells treated with c9, t11-CLA (%)
C9,t11-CLA(μmol/L)24 h
48 h
bcl-2Fasc-mycbcl-2Fasc-myc
06.800.605.508.000.455.30
254.3004.858.050.854.75
502.50b04.20a3.80b2.75b3.70a
1001.45b1.95b3.80a0.30b4.10b1.35b
2000.15b2.75b2.20b05.95b0.30b