Abnormal β-catenin gene expression with invasiveness of primary hepatocellular carcinoma in China

Table 1 Labeling index for β-catenin accumulated type and membraneous type in HCC and para-cancerous tissues (n = 34, x^-± s)

Tissue	Membraneous	Accumulated
HCC	59.9 ± 26.3	24.6 ± 8.5
Para-cancerous tissue	18.3 ± 9.7b	91.8 ± 10.6b

^bP < 0.01 vs HCC.

Table 2 Relationship between labeling index of β-catenin accumu-lated type, expression index of β-catenin mRNA and clinicopatho-logical characteristics of HCC

	n	LI of β-catenin accumulated type	EI of β-catenin mRNA
Male	31	58.4 ± 14.2	0.8 ± 0.2
Female	3	54.1 ± 15.3	0.9 ± 0.1
AFP ≤ 20 ng/mL	9	49.3 ± 17.2	0.8 ± 0.1
AFP > 20 ng/mL	25	54.3 ± 13.7	0.8 ± 0.1
Tumor size
≤ 5 cm	15	58.7 ± 20.4	0.8 ± 0.2
5 cm~10 cm	7	54.4 ± 21.3	0.8 ± 0.2
> 10 cm	12	55.9 ± 17.9	0.8 ± 0.1
Capsule
Complete	15	72.2 ± 23.4	0.7 ± 0.1
Incomplete	19	44.4 ± 21.1b	0.9 ± 0.1a
Intrahepatic Metastasis Yes	14	77.2 ± 25.5	0.9 ± 0.2
Intrahepatic Metastasis No	20	41.3 ± 19.6b	0.7 ± 0.1a
Portal vein thrombus Yes	19	79.8 ± 14.9	0.9 ± 0.2
Portal vein thrombus No	15	52.8 ± 25.9a	0.6 ± 0.2a
Edmondson’s Grade II	19	39.7 ± 20.0	0.7 ± 0.4
Edmondson’s Grade III	15	75.9 ± 18.7b	0.8 ± 0.2
Cirrhotic nodule ≤ 0.5 cm	23	54.3 ± 12.5	0.8 ± 0.2
Cirrhotic nodule >0.5 cm	11	62.2 ± 16.6	0.8 ± 0.1

^aP < 0.05,

^bP < 0.01.