Preliminary results of Thymosin-a1 vs interferon-α treatment in patients with HBeAg negative and serum HBV DNA positive chronic hepatitis B

Table 1 Responses to treatment in patients with chronic hepatitis B

	T-a1 (n = 18)	IFN-α (n = 30)	HC (n = 30)
	After 6 mo of treatment		After 6 mo of follow-up
ALT normalization	7 (38.9%)	15 (50%)	3 (10%)
HBV DNA-negative	9 (50%)b	18 (60%)b	2 (6.7%)
ALT normal/HBV	6 (33.3%)	14 (46.7%)b	1 (3.3%)
DNA-negative
	After 6 mo of follow-up		After 12 mo of follow-up
ALT normalization	12 (66.7%)ab	10 (33.3%)	2 (6.7%)
HBV DNA-negative	12 (66.7%)ab	9 (30%)	2 (6.7%)
ALT normal/HBV	10 (55.6%)ab	7 (23.3%)	1 (3.3%)
DNA-negative

^aP < 0.05, vs IFN-α;

^bP < 0.01, vs HC.