Effect of gastrectomy on G-cell density and functional activity in dogs

Table 1 Effects of different operative procedures on gastric acid secretion

Operation	Group	Preoperation (mmol/h)	Postoperation (mmol/h)	Inhibiting rate (%)
DPG-BII	BAO	1.80 ± 0.25	0.48 ± 0.20b	73.7
	MAO	5.19 ± 0.56	1.04 ± 0.19b	80.0
PPG	BAO	2.25 ± 0.27	0.98 ± 0.26a	56.4
	MAO	4.49 ± 0.34	1.76 ± 0.19b	60.7
HSV	BAO	2.19 ± 0.21	0.97 ± 0.26a	55.9
	MAO	5.30 ± 0.14	1.29 ± 0.47b	75.7

^aP < 0.05;

^bP < 0.01, vs preoperation.

Table 2 Effects of different operative procedure on serum gastrin level

Operation	Group	Pre-operation (ng/L)	Post-operation (ng/L)	Changing rate (%)
DPG-BII	fasting	179 ± 104	90 ± 117a	↓49.7
	postprandial	181 ± 86	94 ± 39a	↓48.8
PPG	fasting	190 ± 153	144 ± 63	↓25.9
	postprandial	239 ± 115	180 ± 47	↓24.4
HSV	fasting	100 ± 10	166 ± 75	↑65.2
	postprandial	103 ± 48	186 ± 63	↑54.1

^aP < 0.05, vs preoperation.

Table 3 Effects of different operative procedure on G cell density

Operation	Site	Preoperation (cell/field)	Postoperation (cell/field)	Incerasing rate (%)
DPG-BII	Duodenum	23.1 ± 5.0	41.3 ± 4.9b	78.9
	Jejunum	1.1 ± 1.1	3.2 ± 3.0	190.4
PPG	Antrum	66.2 ± 2.1	103.3 ± 18.8a	56.0
	Duodenum	15.6 ± 5.3	27.1 ± 3.6a	74.3
	Jejunum	1.0 ± 4.2	1.1 ± 1.9	11.0
HSV	Antrum	69.8 ± 23.2	103.3 ± 19.3b	47.6
	Duodenum	33.7 ± 15.1	60.1 ± 21.5	78.5
	Jejunum	5.5 ± 3.3	17.3 ± 9.2	218.3

^aP < 0.05;

^bP < 0.01, vs preoperation.

Table 4 Effects of different operations on G cell function

Operation	Site	Group	1+	2+	3+	4+
DPG-BII	Duodenum	Preoperation	21	142	106	29
		Postoperation	24	73	157	46b
PPG	Antrum	Preoperation	32	136	71	61
		Postoperation	23	115	64	98a
	Duodenum	Preoperation	50	124	81	45
		Postoperation	24	93	117	68b
HSV	Antrum	Preoperation	55	105	84	56
		Postoperation	38	94	73	95a
	Duodenum	Preoperation	67	107	74	52
		Postoperation	24	99	81	96b

^aP < 0.05;

^bP < 0.01, vs preoperation.