Reduced gastric acid production in burn shock period and its significance in the prevention and treatment of acute gastric mucosal lesions

Table 1 The postburn changes of gastric acid production in rats (^-x ± s)

Groups	Animals	Volume (mL/3h)	Total acidity (mmol/L)	Total acid output (μmol/h)
Control	10	4.41 ± 0.88	97.36 ± 14.40	140.14 ± 16.84
PBH3	10	1.65 ± 0.24b	60.28 ± 10.46b	32.84 ± 6.14b
PBH6	10	1.07 ± 0.19b	43.78 ± 4.59b	15.47 ± 2.21b
PBH12	10	0.63 ± 0.20b	10.81 ± 2.58b	2.23 ± 0.73b
PBH24	10	2.58 ± 0.39b	86.89 ± 12.21a	75.45 ± 18.69b
PBH48	10	2.52 ± 0.20b	82.34 ± 12.82b	69.28 ± 12.92b

^aP < 0.05,

^bP < 0.01 vs control.

Table 2 The postburn changes of gastric mucosal blood flow in rats (mL/min·g, ^-x ± s)

Groups	Animals	GMBF	Groups	Animals	GMBF
Control	6	0.89 ± 0.25	PBH12	6	0.24 ± 0.05b
PBH3	6	0.36 ± 0.12b	PBH24	6	0.54 ± 0.11b
PBH6	6	0.31 ± 0.05b	PBH48	6	0.71 ± 0.17a

^aP < 0.05,

^bP < 0.01 vs control.

Table 3 The postburn changes of ATP, ADP, AMP and EC in gastric muco sa in rats (^-x ± s)

Groups	Animals	ATP(μmol/g)	ADP(μmol/g)	AMP(μmol/g)	EC
Control	6	4.76 ± 0.41	2.58 ± 0.18	1.06 ± 0.09	0.72 ± 0.02
PBH3	6	3.53 ± 0.24b	2.37 ± 0.17	1.39 ± 0.15a	0.65 ± 0.02b
PBH6	6	3.16 ± 0.40b	2.03 ± 0.23b	1.99 ± 0.24b	0.58 ± 0.03b
PBH12	6	2.38 ± 0.34b	1.56 ± 0.17b	2.64 ± 0.31b	0.48 ± 0.03b
PBH24	6	3.41 ± 0.38b	2.26 ± 0.22a	1.73 ± 0.26b	0.62 ± 0.02b
PBH48	6	3.96 ± 0.37b	2.34 ± 0.26	1.69 ± 0.15b	0.64 ± 0.01b

^aP < 0.05,

^bP < 0.01 vs control.