nm23 expression in gastric carcinoma and its relationship with lymphoproliferation

Table 1 Results of positive expression of nm23, hyperplasia of lymphatic tissue and metastasis in various types of gastric carcinoma

Type of cancer	Number of cases	Positive expression of nm23 cases (%)	Enlarged lymph nodes (nodes)	Reactive hyperplasia of lymph nodes (nodes)	Cancer metastasis of lymph nodes (nodes)				Lymphocytes around cancer (cases)
					I	II	III	IV	-	+	++	+++
Papillary adenocarcinoma	8	7(87.5)	3 4	26	2	4	2	0	1(12.5)	3(37.5)	3(37.5)	1(12.5)
Tubular adenocarcinoma	17	14(82.4)	105	38	4	28	29	6	0(0.0)	3(17.6)	8(47.1)	6(35.3)
Poorly differentiated adenocarcinoma	37	30(81.1)	163	97	2	16	29	19	4(10.8)	7(45.9) 11(29.7)		5(13.5)
Mucinous adenocarcinoma	23	16(69.6)	8 9	35	1	14	26	13	3(13.0) 12(52.2)		6(26.1)	2(8.7)
Signet ring cell carcinoma	12	9(75.0)	9 1	18	2	24	32	15	1(12.5)	6(50.0)	5(41.7)	0(0.0)
Total	97	76(78.4)	482	214	1	86	118	53	9(9.3)	41(42.3)	33(34.0)	14(14.4)

Table 2 Relationship between stage of gastric cancer and expression of nm23 and hyperplasia of lymphatic tissue

Group	No. of cases	Positive nm23 expression No. (%)	Lymphocytes around cancer cases (%)	Reactive hyperplasia of lymph nodes (nodes)	Metastatic lymph nodes (nodes)
T 1	6	6(100.0)	6(100.0)	48	0
T 2	15	14(93.3)	14(93.3)	52	4
T 3	27	24(85.2)	25(92.6)	63	19
T 4	49	33(67.3)	43(97.8)	51	245
Total	97	76(78.4)	88(90.7)	214	268