Hepatic microenvironment underlies fibrosis in chronic hepatitis B patients

Table 1 Clinicopathological features of the chronic hepatitis B patients included in this study

Parameters	Chronic hepatitis B		P value1
	No or mild fibrosis	Advanced fibrosis
	(S0-1, n = 16)	(S3-4, n = 16)
Gender			0.716
Male	11	9
Female	5	7
Age (yr)			0.479
< 45	9	6
≥ 45	7	10
ALT (U/L)			0.704
< 50	12	10
≥ 50	4	6
HBV-DNA (copies/mL)			0.479
< 105	10	7
≥ 105	6	9
Inflammation			0.037
G1-2	15	9
G3-4	1	7

¹Fisher’s exact test. ALT: Alanine aminotransferase; HBV: Chronic hepatitis B virus.