Golimumab in real-world practice in patients with ulcerative colitis: Twelve-month results

Table 1 Demographic and disease-specific properties

	mITT (n = 282)	mITTe (n = 212)
Gender (male/female), %	47.2/52.8	47.6/52.4
Age (mean ± SD)	40.8 (± 13.9)	39.7 (± 12.1)
Marital status
Single	116 (41.1)	88 (41.5)
Married/living together	156 (55.3)	117 (55.2)
Divorced	8 (2.8)	7 (3.3)
Widowed	2 (0.7)	-
Rectal bleeding
No blood seen	95 (33.7)	68 (32.1)
Streaks of blood with stool less than half the time	81 (28.7)	55 (25.9)
Obvious blood with stool most of the time	81 (28.7)	69 (32.5)
Blood alone passes	25 (8.9)	20 (9.4)
Physician global assessment
Normal	8 (2.8)	7 (3.3)
Mild disease	54 (19.1)	39 (18.4)
Moderate disease	173 (61.3)	131 (61.8)
Severe disease	47 (16.7)	35 (16.5)
Alcohol consumption (actual)
Yes/no	142 (50.4)/140 (49.6)	114 (53.8)/98 (46.2)
Concomitant disease
Yes/no	121 (42.9)/161 (57.1)	82 (38.7)/130 (61.3)
Frequency of alcohol consumption
Occasional	117 (82.4)	95 (83.3)
Once a week	11 (7.7)	10 (8.8)
Several times a week	9 (6.3)	5 (4.4)
Daily	5 (3.5)	4 (3.5)
Nicotine consumption (actual)
Yes/no	28 (9.9)/254 (90.1)	22 (10.4)/190 (89.6)
Abuse of other substances
Yes/no	1 (0.4)/281 (99.6)	1 (0.5)/281 (99.5)
Cannabis	1 (100)	1 (100.0)

Data are shown as n (%), except where otherwise mentioned. mITT: Total analysis population; mITTe: Employed analysis population.

Table 2 Occupational status

	mITT (n = 282)	mITTe (n = 212)
Occupational status
Employed (full time)	172 (61.0)	172 (81.1)
Employed (part time)	39 (13.8)	39 (18.4)
Retired	13 (4.6)	1 (0.5)1
Full reduced	12 (4.3)
Not working	46 (16.3)
Part time employment due to
Ulcerative colitis	7 (17.9)	7 (17.9)
Other reason	32 (82.1)	32 (82.1)
Full reduced due to
Ulcerative colitis	8 (66.7)	N/A
Other reason	4 (33.3)	N/A

¹One subject who stated “retired” on the electronic case report form was included, because she had entries in the work productivity and activity impairment. It was assumed that this subject actually worked part-time. Data are shown as n (%). mITT: Total analysis population; mITTe: Employed analysis population; N/A: Not applicable.

Table 3 Selected concomitant medications

	mITT (n = 282)	mITTe (n = 212)
Any medication	125 (44.3)	90 (42.5)
Corticosteroids	123 (43.6)	88 (41.5)
Thiopurines
Azathioprin	4 (1.4)	4 (1.9)

Data are shown as n (%). mITT: Total analysis population; mITTe: Employed analysis population.