Gender differences in vascular reactivity of mesenteric arterioles in portal hypertensive and non-portal hypertensive rats

Table 1 Maximal responses and effective concentrations causing EC₅₀ of mesenteric arterioles to NE in the four male groups

	SO control	ORX control	SO PHT	ORX PHT
Emax, %	80.95 ± 6.18	78.71 ± 4.8	56.93 ± 15.33a	52.76 ± 10.29c
EC50, 10-6 mol/L	2.51 ± 0.63	4.17 ± 2.45	4.77 ± 2.17a	4.31 ± 2.89

^aP < 0.05 vs SO control rats;

^cP < 0.05 vs SO control rats. PHT: Portal hypertension; SO: Sham operation; ORX: Orchiectomy; Emax: Maximal responses; EC₅₀: Effective concentrations causing half maximum responses.

Table 2 Maximal responses and effective concentrations causing EC₅₀ of mesenteric arterioles to NE in the four female groups

	SO control	OVX control	SO PHT	OVX PHT
Emax, %	77.27 ± 6.37	74.84 ± 5.91	64.71 ± 7.53a	53.70 ± 10.49ace
EC50, 10-6 mol/L	4.22 ± 1.97	3.50 ± 1.48	7.14 ± 7.71	7.78 ± 9.28

^aP < 0.05 vs SO control rats;

^cP < 0.05 vs OVX control rats;

^eP < 0.05 vs SO PHT rats. PHT: Portal hypertension; SO: Sham operation; OVX: Ovariectomized; E_max: Maximal responses; EC₅₀: Effective concentrations causing half maximum responses.