Observational Study
Copyright ©The Author(s) 2019.
World J Gastroenterol. Apr 14, 2019; 25(14): 1753-1763
Published online Apr 14, 2019. doi: 10.3748/wjg.v25.i14.1753
Table 1 Clinical characteristics of the study subjects
CEAS (n = 20)CD (n = 98)P value1
Age, yr56 (41-63)44 (38-54)0.098
Gender
Male5 (25)66 (67)0.0008
Female15 (75)32 (33)
Smoking
Never smoker16 (80)68 (69)0.42
Current smoker1 (5)13 (13)
Former smoker3 (15)17 (18)
Pulmonary disease1 (5)5 (5)1
History of surgery13 (65)59 (60)0.8
CRP, g/dL0.30 (0.11-0.53)0.13 (0.03-0.58)0.26
Disease location
L1, ileal34 (35)
L2, colonic14 (14)
L3, ileocolonic50 (51)
Disease duration, yr33 (19-42)20 (13-29)0.0055
Table 2 Factors associated with prostaglandin E major urinary metabolite concentrations
Univariable linear regression (P value)
AgeP = 0.47 (0.067)
Gender (1, female; 0, male)P = 0.26 (0.10)
Smoking (1, Current or former smoker; 0, Never smoker)P = 0.17 (-0.13)
Pulmonary diseaseP < 0.0001 (0.36)
History of surgeryP = 0.029 (0.20)
CRPP = 0.078 (0.16)
Disease durationP = 0.0040 (0.26)
Table 3 Convert odds ratio for prostaglandin E major urinary metabolite
Model 1Model 2Model 3
Odds ratio of 1 log unit change7.3629.6
(95%CI)(3.2-16.7)(2.6-13.9)(4.7-185.7)
AUC (95%CI)0.90 (0.82-0.94)0.93 (0.87-0.96)0.95 (0.86-0.98)

  • Citation: Matsuno Y, Umeno J, Esaki M, Hirakawa Y, Fuyuno Y, Okamoto Y, Hirano A, Yasukawa S, Hirai F, Matsui T, Hosomi S, Watanabe K, Hosoe N, Ogata H, Hisamatsu T, Yanai S, Kochi S, Kurahara K, Yao T, Torisu T, Kitazono T, Matsumoto T. Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations. World J Gastroenterol 2019; 25(14): 1753-1763
  • URL: https://www.wjgnet.com/1007-9327/full/v25/i14/1753.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v25.i14.1753