Basic Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Nov 7, 2018; 24(41): 4663-4678
Published online Nov 7, 2018. doi: 10.3748/wjg.v24.i41.4663
Table 1 Patient and tumour characteristics
CharacteristicsIHC and IF cohortISH cohort
AgeMean (yr)67.067.9
Tumour differentiation grade
Well differentiated (G1)n00
Moderately differentiated (G2)n819
Poorly differentiated (G3)n02
T Stage2T1/T2/T3/T40/0/8/00/0/20/1
N stage2N0/N12/65/16
Surgical procedure
Whipple resectionn516
Left-sided pancreatectomyn35
Table 2 Simplified scheme of the expression profiles of 7 of 45 markers that showed a statistically significant difference in expression between the juxtatumoural stroma and peripheral stroma
Fibroblast markers
ECM marker
α-SMACD10CD271CytoglobinDOG1miR-21NestinTenascin C
Juxtatumoural stroma++++++++++++++++++++++
Peripheral stroma+++++++++-+++
Lobular stroma++++++++++++++++++
Septal stroma++++++++++++++
Expression in other cells in PC
Adenocarcinoma cells----+++--
Endothelial cells------+++-
Mast cells--------
Media myocytes++++-+++-----
Neutrophilic granulocytes-++------