Right- and left-sided colorectal cancers respond differently to traditional Chinese medicine

Table 1 Levels of sIL-2R, ALT, and HBV DNA in the sera of patients with chronic HBV infection (mean ± SD)

	Left-sided		Right-sided
	TCM ,n = 404	Non-TCM ,n = 213	TCM,n = 132	Non-TCM,n = 68	P value
Gender					0.035a
Man	207	126	63	28
Woman	197	87	69	40
Age (yr)					0.027a
< 60	163	70	41	17
≥ 60	241	143	91	51
Histodifferentiatio, n					0.293
Poorly	47	19	18	8
Moderately	252	123	80	34
Well	9	7	6	2
Unknown	96	64	28	24
Lympho node metastasis					0.125
Yes	176	74	57	32
No	228	139	75	36
TNM stage					0.331
I	77	38	19	8
II	148	95	54	28
III	179	80	59	32
Chemotherapy					0.000a
Yes	332	149	97	44
No	72	64	35	24
Radiotherapy					0.011a
Yes	44	19	5	1
No	360	194	127	67
Diabetes					0.995
Yes	61	33	21	10
No	343	180	111	58
Hypertension					0.872
Yes	131	76	44	22
No	273	137	88	46
Heart disease					0.367
Yes	38	30	15	7
No	366	183	117	61
Stroke					0.049a
Yes	22	13	1	2
No	382	200	119	66

^aP < 0.05 statistical difference. LSCRC: Left-sided colorectal cancer; RSCC: Right-sided colon cancer.

Table 2 Cox analysis for disease-free survival in left- and right-sided colorectal cancer

	Left-sided colorectal cancer			Right-sided colon cancer
	Univariate	Multivariate		Univariate	Multivariate
	P value	P value	HR (95%CI:)	P value	P value	HR (95%CI:)
Gender	0.024a	0.079	0.81 (0.63-1.02)	0.339	0.023a	0.63 (0.42-0.94)
Age	0.955	0.792	1.04 (0.80-1.34)	0.712	0.612	1.12 (0.72-1.76)
Histodifferentiation	0.648	0.016a	1.16 (1.03-1.31)	0.685	0.407	1.09 (0.89-1.33)
TNM stage	0.000a	0.000a	2.39 (1.96-2.90)	0.000a	0.000a	2.63 (1.85-3.72)
TCM	0.000a	0.000a	0.53 (0.41-0.67)	0.003a	0.000a	0.47 (0.31-0.71)
Diabetes	0.948	0.716	0.94 (0.66-1.32)	0.240	0.200	0.67 (0.36-1.24)
Hypertention	0.650	0.120	1.24 (0.94-1.64)	0.019a	0.005a	0.51 (0.31-0.81)
Heart disease	0.710	0.988	1.00 (0.66-1. 50)	0.461	0.155	1.57 (0.84-2.93)
Stroke	0.171	0.091	0.60 (0.33-1.09)	0.681	0.449	1.34 (0.63-2.83)

^aP < 0.05 statistical difference.