Editorial
Copyright ©The Author(s) 2017.
World J Gastroenterol. Apr 28, 2017; 23(16): 2826-2831
Published online Apr 28, 2017. doi: 10.3748/wjg.v23.i16.2826
Table 1 Required time for acute pancreatitis diagnosis n (%)
2003 Survey2007 Survey2011 SurveyP value
Time for diagnosis
(Total AP)
≤ 12 h707 (51.6)806 (58.8)1148 (61.7)< 0.00011
13-24 h288 (21.0)252 (18.4)359 (19.3)
25-48 h156 (11.4)150 (10.9)195 (10.5)
49-72 h95 (6.9)70 (5.1)69 (3.7)
≥ 73 h124 (9.1)94 (6.8)89 (4.8)
Time for diagnosis (Severe AP)
≤ 12 h148 (53.1)170 (60.9)240 (66.8)0.0031
13-24 h54 (19.3)51 (18.3)71 (19.8)
25-48 h35 (12.5)31 (11.1)25 (7.0)
49-72 h20 (7.2)15 (5.4)13 (3.6)
≥ 73 h22 (7.9)12 (4.3)10 (2.8)
Table 2 Prophylactic administration of antibiotics within 24 h n (%)
2003 survey2007 survey2011 surveyP value
Antibiotics (Total AP)
Carbapenem280 (27.7)327 (32.5)689 (36.9)< 0.00011
Cephem270 (26.7)264 (26.2)485 (26.0)
Cephem/β-lactamase inhibitor combination429 (42.4)390 (38.8)641 (34.4)
Others33 (3.2)25 (2.5)51 (2.7)
Antibiotics (Severe AP)
Carbapenem86 (41.2)107 (52.2)286 (67.3)< 0.00011
Cephem54 (25.8)36 (17.6)48 (11.3)
Cephem/β-lactamase inhibitor combination62 (29.7)57 (27.8)80 (18.8)
Others7 (3.3)5 (2.4)11 (2.6)
Table 3 Enteral nutrition n (%)
Enteral nutrition(Total AP)2007 survey2011 surveyP value
Yes72 (4.7)135 (6.2)0.051
No1466 (95.3)2053 (93.8)
Enteral nutrition (Severe AP)2007 survey2011 surveyP value
Yes45 (14.6)97 (22.4)0.0081
No264 (85.4)337 (77.6)
Enteral nutrition (Severe AP in 2011 survey)< 500 beds500 beds or moreP value
Yes14 (9.9)83 (28.4)< 0.00011
No127 (90.1)209 (71.6)
Table 4 Trend in continuous regional arterial infusion n (%)
2003 survey2007 survey2011 surveyP value
CRAI (Total AP)
Yes118 (18.0)72 (4.5)95 (4.3)< 0.00011
No538 (82.0)1530 (95.5)2129 (95.7)
CRAI (Severe AP)
Yes72 (22.4)51 (14.6)76 (17.2)0.0271
No249 (77.6)299 (85.4)365 (82.8)
Table 5 Continuous regional arterial infusion and mortality
CRAI2003 survey2007 survey2011 survey
(Severe AP)MortalityMortalityMortality
Yes15/71 (21.1)5/49 (10.2)7/74 (9.5)
No23/238 (9.7)27/279 (9.7)35/327 (10.7)
P value0.009810.9090.752
Table 6 Factors affecting walled-off necrosis development in severe acute pancreatitis in 2011 survey
WON (+)WON (-)P value
Diagnosis within 48 h14/17 (82.4)60/63 (95.2)0.074
Average amount of fluid resuscitation (mL)4865.8 ± 2130.24661.1 ± 2758.30.765
Enteral nutrition14/22 (63.6)24/72 (33.3)0.0111
CRAI11/23 (47.8)21/75 (28.0)0.076
Table 7 Factors affecting surgery requirement in severe acute pancreatitis in 2011 survey
Surgery (+)Surgery (-)P value
Diagnosis within 48 h16/18 (88.9)279/300 (94.6)0.513
Average amount of fluid resuscitation (mL)6183.6 ± 4109.54203.1 ± 2810.60.0031
Enteral nutrition13/25 (52.0)76/350 (21.7)0.00062
CRAI8/25 (32.0)62/360 (17.2)0.064
Table 8 Factors affecting late (> 4W) acute pancreatitis -related death in severe acute pancreatitis in 2011 survey
AP-related death (> 4W)AliveP value
Diagnosis within 48 h5/8 (62.5)286/305 (98.3)0.0131
Average amount of fluid resuscitation (mL)5525.0 ± 3415.54295.5 ± 2914.70.154
Enteral nutrition6/12 (50.0)85/354 (24.0)0.081
CRAI0/12 (0.0)76/355 (21.4)0.138