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Copyright ©The Author(s) 2016.
World J Gastroenterol. Oct 7, 2016; 22(37): 8294-8303
Published online Oct 7, 2016. doi: 10.3748/wjg.v22.i37.8294
Table 1 Summary of survival outcomes for presumed nonalcoholic fatty liver disease-hepatocellular carcinoma undergoing curative therapies
First authorStudy designStudy periodStudy locationNumber of NAFLD-HCC casesTreatment1Survival outcomes
Overall survivalDisease-free survival
ReddyRetrospective cohort2000-2010Single-centered (United States)52OLT, resection, RFA21-yr: 90%31-yr: 84%3
3-yr: 72%33-yr: 70%3
5-yr: 65%35-yr: 60%3
WongRetrospective cohort2002-2012Multi-centered (United States)NA4OLT1-yr: 87.5%NA
3-yr: 79.8%
5-yr: 65.5%
PiscagliaProspective cohort2010-2012Multi-centered (Italy)49OLT, resection, RFA1-yr: 90%-95%3NA
3-yr: 85%-90%3
MalikRetrospective cohortNASingle-centered (United States)17OLT1-yr: 85%-90%3NA
Hernandez-AlejandroRetrospective cohort2000-2011Single-centered (Canada)17OLTNA1-yr: 95%3
3-yr: 95%3
5-yr: 85%3
CauchyRetrospective cohort2000-2011Single-centered (France)625Resection1-yr: 83%1-yr: 83%
3-yr: 75%3-yr: 70%
WakaiRetrospective cohort1990-2007Single-centered (Japan)17Resection5-yr: 59%5-yr: 66%
TakumaRetrospective cohort1992-2009Single-centered (Japan)366Resection, RFA, PEI, MCT1-yr: 94%1-yr: 89%
3-yr: 85%3-yr: 68%
5-yr: 54%5-yr: 54%