Trajectories of endoscopic Barrett esophagus: Chronological changes in a community-based cohort

Table 1 Background patient demographics

Mean age, yr (mean ± SD, range)	68.1 ± 10.8 (27-95)
Gender (male/female)	326/453 (41.8/58.2)
Antiacid therapy (present/absent)	292/487 (37.5/62.5)
GERD-suggested symptoms (present/absent)	414/365 (53.1/46.9)
Esophagitis (present/absent)	81/698 (10.4/89.6)
Hiatus hernia (present/absent)	704/75 (90.4/9.6)

Number (%) of patients otherwise stated (n = 779). GERD: Gastroesophageal reflux disease.

Table 2 Factors associated with appearance or regression of e short segment Barrett esophagus

		Appearance		Complete regression
		Hazard ratio (95%CI)	P value	Hazard ratio (95%CI)	P value
Age		0.98 (0.96-1.00)	0.11	1.00 (0.98-1.02)	0.750
Gender	Male	1		1
	Female	1.01 (0.63-1.62)	0.98	1.32 (0.88-1.97)	0.180
Antiacid therapy	Absent	1		1
	Present	1.19 (0.74-1.93)	0.47	0.73 (0.48-1.14)	0.170
GERD-suggested symptoms	Absent	1		1
	Present	0.77 (0.46-1.19)	0.22	0.98 (0.64-1.50)	0.920
Esophagitis	Absent	1		1
	Present	1.09 (0.55-2.15)	0.80	0.51 (0.26-1.01)	0.052
Hiatus hernia	Absent	1		1
	Present	8.66 (1.20-62.6)	0.03	0.13 (0.03-0.58)	0.007

Multivariable Cox regression analysis. GERD: Gastroesophageal reflux disease.