Protein and gene expression characteristics of heterogeneous nuclear ribonucleoprotein H1 in esophageal squamous cell carcinoma

Table 1 Expression of heterogeneous nuclear ribonucleoprotein H1protein and its clinical significance in 125 esophageal squamous cell carcinomaspecimens n (%)

Characteristics	All cases (n)	HNRNPH1			P value1
		Negative	Weak	Strong
Tissues
Normal	125	53 (42.4)	44 (35.2)	28 (22.4)	0.0005
Cancer	125	49 (39.2)	22 (17.6)	54 (43.2)
Age (yr)					0.5422
≥ 60	71	26 (36.6)	16 (22.5)	29 (40.8)
< 60	54	23 (42.6)	6 (11.1)	25 (46.3)
Gender					0.9615
Male	90	34 (37.8)	17 (18.9)	39 (43.3)
Female	35	15 (42.9)	5 (14.2)	15 (42.9)
Tumor differentiation					0.0652
Well	29	15 (51.7)	5 (17.2)	9 (31.1)
Moderately	72	26 (36.1)	16 (22.2)	30 (41.7)
Poorly	24	8 (33.3)	1 (4.2)	15 (62.5)
Tumor differentiation					0.0337
Well + moderately	101	41 (40.6)	21 (20.8)	39 (38.6)
Poorly	24	8 (33.3)	1 (4.2)	15 (62.5)
Lymph Node Metastasis2					0.1839
Present	42	14 (33.3)	9 (21.4)	19 (45.2)
Not present	36	18 (50.0)	7 (19.4)	11 (30.6)

¹The strong expression of HNRNPH1 was compared with negative and weak expression;

²Only 78 cases had information on lymph node metastasis. HNRNPH1: Heterogeneous nuclear ribonucleoprotein H1; ESCC: Esophageal squamous cell carcinoma.