MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling

doi:10.3748/wjg.v22.i29.6652

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2016; 22(29): 6652-6662
Published online Aug 7, 2016. doi: 10.3748/wjg.v22.i29.6652

Table 1 List of miRNAs interacting with hedgehog signaling in liver fibrosis

miRNA(s)	Expression	Target gene(s)	Sample type(s)	Ref.
miR-378a-3p	Downregulated	Gli3	CCl₄-induced mouse fibrotic liver/Primary mouse HSC	[50]
miR-200a	Downregulated	Gli2	Rat HSC	[76]
miR-125b	Downregulated	Smo	CCl₄-induced rat fibrotic liver/Primary rat HSC	[77]
miR-152	Downregulated	DNMT1	CCl₄-induced mouse fibrotic liver/Primary mouse HSC	[75]
miR-29	Downregulated	-	MCDE-dieted mouse liver	[71]

HSC: Hepatic stellate cell.

Citation: Hyun J, Jung Y. MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling. World J Gastroenterol 2016; 22(29): 6652-6662
URL: https://www.wjgnet.com/1007-9327/full/v22/i29/6652.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i29.6652