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Copyright ©The Author(s) 2016.
World J Gastroenterol. Jun 21, 2016; 22(23): 5301-5316
Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5301
Table 1 Pathological changes in various mice after azoxymethane/dextran sulfate sodium treatment
Ingested DSS concentrationBody weight loss(> 20%)Granulocyte infiltration (> 400/field)Fibroblast accumulation (> 20% type I collagen+ areas)Tumor numbers
Wild-type mice3.0%+++> 20
CCR1-deficient mice3.0%---< 5
4.5%+++> 20
CCR5-deficient mice3.0%---< 5
4.5%++-< 7
CCL3-deficient mice3.0%---< 5
4.5%++-< 5