Retrospective Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Apr 14, 2016; 22(14): 3803-3812
Published online Apr 14, 2016. doi: 10.3748/wjg.v22.i14.3803
Table 1 Baseline characteristics of all patients
CharacteristicMet the Milan criteria (n = 109)
Did not meet the Milan criteria (n = 59)
Low-dose HBIGHigh-dose HBIGP valueLow-dose HBIGHigh-dose HBIGP value
(n = 62)(n = 47)(n = 33)(n = 26)
Age (yr)53.8 ± 6.453.6 ± 7.60.85454.1 ± 7.453.0 ± 8.70.608
Sex (male/female)49/1335/120.57530/321/50.284
Child-Pugh score7 (5-13)5 (5-12)0.0027 (5-13)6 (5-13)0.226
AFP (ng/mL)18.8 (2.0-8891.8)13.3 (1.8-3811.2)0.40730.7 (3.5-31142.9)235.3 (2.9-57348.8)0.049
Number of tumors1 (1-3)1 (1-3)0.8571 (1-8)1 (1-5)0.743
Largest tumor size (cm)2.2 (0.6-4.5)2.2 (0.8-4.0)0.5045.4 (0.9-13.0)4.9 (1.1-25.0)0.976
Edmond-Steiner grade (I,II/III,IV)26/3621/260.7748/252/240.161
Major vessel invasion (absent/present)62/047/0N/A26/717/90.250
Microvascular invasion (absent/present)42/17[3]30/170.42011/226/200.388
Bile duct invasion (absent/present)61/142/20.57731/223/30.646
Satellite nodule (absent/present)46/15[1]37/100.68614/1911/150.993
Table 2 Baseline characteristics of propensity-matched patients with low- and high-dose Hepatitis B Immunoglobulin who met and did not meet the Milan criteria
CharacteristicMet the Milan criteria (38 pairs)
Did not meet the Milan criteria (18 pairs)
Low-dose HBIGHigh-dose HBIGP valueLow-dose HBIGHigh-dose HBIGP value
(n = 38)(n = 38)(n = 18)(n = 18)
Age (yr)52.7 ± 5.553.4 ± 8.10.64352.9 ± 8.053.3 ± 8.60.917
Sex (male/female)32/629/90.45316/216/21.000
Child-Pugh score6 (5-12)6 (5-12)0.7106 (5-13)6 (5-13)0.932
AFP (ng/mL)22.6 (2.0-8891.8)15.3 (1.8-3811.2)0.65834.6 (3.5-31142.9)112.5 (2.9-57348.8)0.500
Number of tumors1 (1-3)1 (1-3)0.9631 (1-5)1 (1-5)0.811
Largest tumor size (cm)2.2 (0.8-4.5)2.1 (0.8-4.0)0.9945.75 (1.6-13.0)4.9 (1.1-25.0)0.393
Edmond-Steiner grade (I, II/III, IV)17/2117/211.0004/142/160.500
Major vessel invasion (absent/present)38/038/0N/A12/613/51.000
Microvascular invasion (absent/present)23/1526/120.6645/134/141.000
Bile duct invasion (absent/present)37/137/11.00016/216/21.000
Satellite nodule (absent/present)26/1229/90.6486/125/131.000