Comparison of Stretta procedure and toupet fundoplication for gastroesophageal reflux disease-related extra-esophageal symptoms

Table 1 Baseline characteristics of the study population

Characteristic/parameter	Stretta (n = 47)	LTF (n = 51)	P value
Age (yr)	45.9 ± 10.7	49.7 ± 11.5	0.095
Male ratio, n (%)	19 (40.4)	28 (54.9)	0.163
Symptom score1
Cough	7.7 ± 0.57 (20/47)	7.4 ± 0.82 (25/51)	0.110
Sputum	7.5 ± 0.70 (19/47)	7.4 ± 0.90 (19/51)	0.560
Wheezing	7.7 ± 0.81 (29/47)	7.9 ± 0.93 (33/51)	0.181
Globus hysterics	7.4 ± 0.64 (27/47)	7.2 ± 0.73 (28/51)	0.171

¹The symptom score was designated as the total of the frequency score and the severity score for each symptom. Values are presented as mean ± SD or n (%). LTF: Laparoscopic toupet fundoplication.

Table 2 Post-treatment complications in patients after laparoscopic toupet fundoplication and the Stretta procedure n (%)

	Stretta (n = 47)	LTF (n = 51)	P value
Fever	5 (10.6)	1 (2.0)	0.073
Pharyngeal pain	9 (19.1)	0 (0)	0.0011
Retrosternal discomfort	14 (29.8)	8 (15.7)	0.095
Diarrhea	4 (8.51)	9 (17.6)	0.183
Abdominal distention	0 (0)	5 (9.8)	0.0281
Dysphagia	0 (0)	5 (9.8)	0.0281

¹P value less than 0.05.

Table 3 Post-treatment complications in patients after laparoscopic Toupet fundoplication and the Stretta procedure

Characteristic/parameter value	6-mo follow-up			1-yr follow-up			3-yr follow-up
	Stretta (n = 47)	LTF (n = 51)	P value	Stretta (n = 47)	LTF (n = 51)	P value	Stretta (n = 47)	LTF (n = 51)	P value
Symptom score
cough	3.9 ± 2.55	4.1 ± 2.65	0.780	4.2 ± 2.59	4.3 ± 2.72	0.921	4.6 ± 2.52	4.8 ± 2.36	0.785
Sputum	3.6 ± 2.24	4.0 ± 2.54	0.638	4.0 ± 2.32	4.3 ± 2.60	0.695	4.4 ± 2.29	4.7 ± 2.35	0.628
Wheezing	3.6 ± 2.26	3.9 ± 2.83	0.635	3.7 ± 2.28	3.9 ± 2.86	0.784	4.4 ± 2.23	4.4 ± 2.83	0.982
Globus hysterics	4.7 ± 2.30	3.0 ± 2.53	0.015	4.5 ± 2.38	3.2 ± 2.58	0.040	4.9 ± 2.24	3.2 ± 2.63	0.013
PPI independence, n (%)	32 (68.1)	38 (74.5)	0.510	31 (66.0)	36 (70.6)	0.668	29 (61.7)	33 (64.7)	0.835
Satisfaction	59.26 ± 34.80	72.55 ± 28.50	0.041	56.49 ± 34.78	72.16 ± 28.68	0.016	51.49 ± 32.77	69.80 ± 28.44	0.004

The symptom score was designated as the total of the frequency score and the severity score for each symptom. Values are presented as the mean ± SD or n (%). PPI: Proton pump inhibitor; LTF: Laparoscopic toupet fundoplication.