Retrospective Cohort Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Dec 7, 2015; 21(45): 12843-12850
Published online Dec 7, 2015. doi: 10.3748/wjg.v21.i45.12843
Table 1 Preoperative characteristics of elderly patients undergoing partial colectomy before propensity score matching n (%)
CharacteristicsLaparoscopic colectomy(n = 12009)Open colectomy (n = 15595)P value
Age, mean ± SD75.94 ± 7.1574.87 ± 6.92< 0.001
BMI, mean ± SD27.30 ± 6.3827.17 ± 7.09< 0.001
Gender0.416
Female7401 (61.6)9536 (61.1)
Male4608 (38.4)6059 (38.9)
Procedure< 0.001
Right partial colectomy3122 (25.9)3773 (24.2)
Left partial colectomy6614 (55.1)8492 (54.5)
Sigmoidectomy2273 (19.0)3330 (21.3)
Indication< 0.001
Benign4769 (39.7)5447 (34.9)
Malignant4544 (37.8)7454 (47.8)
Unknown2696 (22.4)2694 (17.3)
ASA class
I155 (1.2)115 (0.7)
II5418 (45.2)4960 (31.8)
III5956 (49.6)9225 (59.2)
IV477 (4.0)1278 (8.2)
V3 (0.02)17 (0.1)
ASA III, IV or V6436 (53.6)10520 (67.5)< 0.001
Alcohol359 (2.9)408 (2.6)0.061
Current smoker  1062 (8.8)1689 (10.8)< 0.001
Cardiac diseases8489 (70.7)11350 (72.8)< 0.001
Hypertension8232 (68.5)10936 (70.1)0.005
History of CHF119 (1.0)297 (1.9)< 0.001
History of MI56 (0.5)169 (1.1)< 0.001
History of angina80 (0.7)200 (1.3)< 0.001
History of PCI957 (8.0)1431 (9.2)< 0.001
History of PCS959 (8.0)1495 (9.6)< 0.001
Pulmonary diseases836 (7.0)1519 (9.7)< 0.001
Dyspnea1600 (13.3)2723 (17.4)< 0.001
History of COPD821 (6.8)1428 (9.2)< 0.001
Ventilator dependent4 (0.02)58 (0.4)< 0.001
Pneumonia20 (0.2)71 (0.5)< 0.001
Neurological disease994 (8.3)1689 (10.8)< 0.001
History of CVA347 (2.9)613 (3.9)< 0.001
History of CVANO355 (3.0)591 (3.8)< 0.001
History of TIA516 (4.3)801 (5.1)0.002
History of tumor CNS11 (0.1)18 (0.1)0.545
Renal diseases62 (0.5)173 (1.1)< 0.001
History of renal failure15 (0.1)56 (0.4)< 0.001
Dialysis dependent52 (0.4)137 (0.9)< 0.001
Bleeding disorders487 (4.1)1009 (6.5)< 0.001
Steroid use1365 (3.0)580 (3.7)0.002
Diabetes3166 (26.4)3193 (20.5)< 0.001
Table 2 Preoperative characteristics of elderly patients undergoing partial colectomy after propensity score matching n (%)
CharacteristicsLaparoscopic colectomy(n = 11008)Open colectomy (n = 11008)P value
Age
mean ± SD75.12 ± 6.9775.21 ± 6.980.857
median ± IQR74 ± 1174 ± 120.332
BMI (mean ± SD)27.31 ± 6.4227.23 ± 7.050.368
Gender0.021
Female6685 (60.7)6852 (62.2)
Male4323 (39.3)4156 (37.8)
Procedure0.013
Right partial colectomy2549 (23.2)2736 (24.8)0.003
Left partial colectomy6237 (56.7)6099 (55.4)0.061
Sigmoidectomy2222 (20.1)2173 (19.8)0.409
Indication< 0.001
Benign4361 (39.6)3966 (36.0)
Malignant4193 (38.1)5431 (49.3)
Unknown2454 (22.3)1611 (14.6)
ASA class
I127 (1.1)110 (1.0)
II4563 (41.5)4563 (41.5)
III5852 (53.2)5673 (51.5)
IV463 (4.2)658 (6.0)
V3 (0.02)4 (0.03)
ASA III, IV or V6318 (57.4)6335 (57.5)0.817
Alcohol341 (3.0)289 (2.6)0.036
Current smoker1051 (9.5)993 (9.0)0.178
Cardiac diseases7905 (71.8)7845 (71.3)0.370
Hypertension7654 (69.5)7614 (69.2)0.559
History of CHF116 (1.1)134 (1.2)0.252
History of MI51 (0.5)57 (0.5)0.563
History of angina75 (0.6)86 (0.7)0.384
History of PCI902 (8.2)807 (7.3)0.017
History of PCS924 (8.4)894 (8.1)0.463
Pulmonary diseases815 (7.4)778 (7.1)0.336
Dyspnea1526 (13.7)1513 (13.7)0.432
History of COPD801 (7.3)758 (6.9)0.259
Ventilator dependent3 (0.02)3 (0.02)1.000
Pneumonia18 (0.2)24 (0.2)0.354
Neurological disease921 (8.4)896 (8.1)0.540
History of CVA333 (3.0)305 (2.8)0.261
History of CVANO323 (2.9)307 (2.8)0.518
History of TIA347 (3.2)353 (3.2)0.818
History of tumor CNS10 (0.1)6 (0.1)0.317
Renal diseases57 (0.5)55 (0.5)0.850
History of renal failure12 (0.1)13 (0.1)0.841
Dialysis dependent49 (0.4)48 (0.4)0.919
Bleeding disorders466 (4.2)425 (3.9)0.161
Steroid use1353 (3.2)318 (2.9)0.170
Diabetes2077 (18.9)2040 (18.5)0.522
Table 3 Intraoperative characteristics of elderly patients undergoing partial colectomy after propensity score matching
CharacteristicsLaparoscopic colectomy(n = 11008)Open colectomy (n = 11008)P value
Operative time (min), mean ± SD151.75 ± 66.15143.56 ± 78.60< 0.001
Anesthesia time (min), mean ± SD209.47 ± 78.54200.72 ± 91.29< 0.001
Blood transfusions, n (%)250 (2.3)307 (2.8)< 0.001
Intraoperative occurrence0.143
Cardiac arrest15
Myocardial infarction35
Unplanned intubation511
Table 4 Post-operative outcomes of elderly patients undergoing partial colectomy after propensity score matching n (%)
CharacteristicsLaparoscopic colectomy(n = 11008)Open colectomy(n = 11008)P valueOR/CI
Overall complications11676 (15.2)2622 (23.8)< 0.0011.56 (1.48-1.65)
Cardiac complications109 (1.0)160 (1.5)0.0021.47 (1.15-1.87)
Cardiac arrest50 (0.4)80 (0.7)0.0081.60 (1.13-2.28)
Myocardial infarction71 (0.6)88 (0.8)0.1761.24 (0.91-1.69)
Pulmonary complications489 (4.4)729 (6.6)< 0.0011.49 (1.33-1.67)
Pneumonia239 (2.2)375 (3.4)< 0.0011.57 (1.34-1.84)
Unplanned intubation217 (2.0)326 (3.0)< 0.0011.50 (1.27-1.78)
Ventilated for more than 48 h165 (1.5)294 (2.7)< 0.0011.78 (1.48-2.15)
Pulmonary emboli69 (0.6 )87 (0.8)0.1481.26 (0.92-1.73)
Deep venous thrombosis97 (0.9)179 (1.6)< 0.0011.85 (1.44-2.36)
Renal complications421 (3.8)656 (6.0)< 0.0011.56 (1.38-1.76)
Progressive renal insufficiency54 (0.4)98 (0.9)< 0.0011.81 (1.30-2.53)
Acute renal failure50 (0.4)72 (0.7)0.0461.44 (1.01-2.06)
Urinary tract infection339 (3.1)524 (4.8)< 0.0011.55 (1.35-1.77)
Infections1170 (10.6)1951 (17.7)< 0.0011.67 (1.56-1.78)
Sepsis274 (2.5)468 (4.3)< 0.0011.71 (1.46-1.98)
Septic shock156 (1.4)284 (2.6)< 0.0011.82 (1.50-2.21)
Superficial incisional infection582 (5.3)968 (8.8)< 0.0011.66 (1.51-1.84)
Deep incisional infection96 (0.9)150 (1.4)0.0011.56 (1.21-2.02)
Organ space infection206 (1.9)347 (3.2)< 0.0011.68 (1.42-1.99)
Wound disruption84 (0.8)144 (1.3)< 0.0011.71 (1.31-2.24)
Return to operating room451 (4.1)588 (5.3)< 0.0011.30 (1.16-1.47)
Length of stay (d), mean ± SD6.61 ± 6.739.62 ± 8.33< 0.001-
30-d mortality173 (1.6)316 (2.9)< 0.0011.83 (1.52-2.19)