Basic Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jul 14, 2015; 21(26): 8061-8072
Published online Jul 14, 2015. doi: 10.3748/wjg.v21.i26.8061
Table 1 Composition of the experimental diets used in this study (g/kg)
Experimental diet
Normal dietHigh-fat diet
Carbohydrate (% of energy)69.8648.45
Protein (% of energy)21.7617.91
Fat (% of energy)8.3833.64
Energy (kcal/100 g)377.19450.52
Ingredient (g/kg)
Cornstarch397.5208.7
Casein200.0200.0
Dextrose132.069.3
Sucrose100.0252.5
Soybean oil70.036.8
Fiber50.026.2
Mineral mix135.018.4
Vitamin mix110.05.3
L-Cystine3.01.6
Choline bitartrate2.51.3
Lard0.0150.0
Cholesterol0.011.0
Calcium hydrogen phosphate0.017.0
Sodium cholate0.02.0
Total10001000
Table 2 Body weight of rats at different time points
GroupWeight (g)
9 d19 d
ND201 ± 7.05254 ± 8.90
HFD199 ± 7.59262 ± 15.09
Table 3 Effects of lutein on lipid metabolism in rats fed a high fat diet
GroupSerum (mmol/L)
Liver (μmol/g)
TCTGLDL-CHDL-CTCTG
ND1.01 ± 0.150.55 ± 0.160.184 ± 0.1340.80 ± 0.090.93 ± 0.062.14 ± 0.44
HFD1.88 ± 0.25b0.57 ± 0.170.566 ± 0.350a0.59 ± 0.15b1.65 ± 0.13b8.28 ± 1.40b
HFD + Lut12.51.95 ± 0.250.45 ± 0.110.515 ± 0.4870.88 ± 0.11d1.74 ± 0.107.09 ± 1.00c
HFD + Lut251.53 ± 0.23d0.51 ± 0.120.305 ± 0.2240.80 ± 0.17d1.66 ± 0.156.41 ± 0.97d
HFD + Lut501.98 ± 0.240.45 ± 0.110.712 ± 0.3420.70 ± 0.111.53 ± 0.08c7.27 ± 1.14