Downregulation of rho-associated protein kinase 1 by miR-124 in colorectal cancer

Table 1 Associations between clinicopathologic factors and miR-124 expression

Parameters	n	miR-124 expression1			P value
		Low	Middle	High
Age					0.823
≤ mean	23	11	8	4
> mean	45	24	16	5
Sex					0.921
Male	47	24	19	4
Female	21	11	5	5
T stage2					0.022
T1	19	4	12	3
T2	17	9	6	2
T3	15	10	3	2
T4	15	12	2	1
N stage2					0.019
N0	23	6	10	7
N1	19	8	7	4
N2	17	8	6	3
N3	9	6	3	0
Metastasis					0.006
Metastasis	30	22	6	2
Non-metastasis	38	14	17	7
Grade3					0.015
Well differentiated	26	10	13	3
Moderately differentiated	12	10	9	3
Poorly differentiated	18	15	1	2

¹Low, T/N < 1.2; middle, T/N = 1.2-10; high, T/N > 10;

²2009 Tumor-Node-Metastasis staging classification system;

³Fuhrman classification system: well differentiated = grade 1 and 2; moderately differentiated = grade 3; and poorly differentiated = grade 4.