Systematic Reviews
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 14, 2014; 20(46): 17595-17602
Published online Dec 14, 2014. doi: 10.3748/wjg.v20.i46.17595
Table 1 Study characteristics
Ref.YearCountryStudy designSample sizeStudy interval (yr)Study population
Polignano et al[24]2008United KingdomNon-randomised prospective cohort502Liver resection
Tsinberg et al[25]2009United StatesNon-randomised prospective cohort3410Liver resection
Rowe et al[26]2009United StatesNon-randomised prospective cohort303Liver resection
Vanounou et al[27]2010United StatesRetrospective cohort736Liver resection
Nguyen et al[28]2011United StatesRetrospective cohort769Liver resection
Bhojani et al[29]2011CanadaRetrospective cohort1444Liver resection
Stoot et al[30]2012NetherlandsRetrospective cohort287Liver resection
Abu Hilal et al[31]2013United KingdomRetrospective cohort1497Liver resection
Cannon et al[32]2013United StatesRetrospective cohort984Liver resection
Kim et al[33]2008South CoreaRetrospective cohort128-Pancreatic resection
Eom et al[34]2008South CoreaRetrospective cohort9311Pancreatic resection
Waters et al[35]2010United StatesRetrospective cohort601Pancreatic resection
Fox et al[36]2008CanadaRetrospective cohort1186Pancreatic resection
Abu Hilal et al[37]2012United KingdomRetrospective cohort516Pancreatic resection
Limongelli et al[38]2012ItalyRetrospective cohort4510Pancreatic resection
Table 2 Assessment of methodological quality
Ref.Level of evidenceMeasurements accuracyDiscountingSensitivity analysisTranslatability to other setting
Polignano et al[24]3●-□○
Tsinberg et al[25]3●-□○
Rowe et al[26]3●-□○
Vanounou et al[27]4●-□○
Nguyen et al[28]4●-□○
Bhojani et al[29]3●-□○
Stoot et al[30]3●-□○
Abu Hilal et al[31]3●-□○
Cannon et al[32]4●-□○
Kim et al[33]4●-□○
Eom et al[34]4●-□○
Waters et al[35]4●-□○
Fox et al[36]4●-□○
Abu Hilal et al[37]4●-□○
Limongelli et al[38]4●-□○
●: Consistent with criteria, low risk of bias; ○: Partly consistent with criteria, unknown risk of bias; □: Not consistent with criteria, high risk of bias; -: Not applicable.
Table 3 Hospital and operative costs of laparoscopic hepatic resection vs open liver resection
Ref. (n)Ward stayHDU/PACUEquipmentTheatreTotal costs
Polignano et al[24] (50)
LLR (25)5535 ± 25761558 ± 19402302 ± 76911539 ± 378920739 ± 5814
OLR (25)8306 ± 55674178± 18781041 ± 66811755 ± 235325285 ± 6750
Tsinberg et al[25] (34)
LLR (18)---28900 ± 211836784 ± 3505
OLR (16)--28023 ± 224747358 ± 3717
Rowe et al[26] (30)
LLR (18)--1071 ± 345--
OLR (12)--851 ± 424--
Vanounou et al[27] (73) 1
LLR (44)----17290
OLR (29)----13962
Nguyen et al[28] (76)2
LLR (34)---1.301.87
OLR (42)---1.001.92
Bhojani et al[29] (144)1
OLR (94)3647652-359811376
LLR (50)5215641-396412523
Stoot et al[30] (28)
OLR (14)2014 ± 510-2113 ± 4873038 ± 7437167 ± 1335
LLR (14)1957 ± 599-2360 ± 3373583 ± 7947901 ± 1107
Abu Hilal et al[31] (149)1
LLR (LRH)(38)238542495579108467139
OLR (ORH)(46)523290222981721018222
OLR (OLLS)(19)173434523947485220579
LLR (LLLS)(46)430019182613655714252
Cannon et al[32] (98)1
OLR (41)---3401949993
LLR (57)---3140054703
Overall studies6062
LLR (310) 22972182935451453819269
OLR (296) 25291585722071140623419
1Values are median (range);
2Nguyen study was excluded from the analysis because raw data were not obtained from the authors. Values are mean ± SD unless indicated otherwise. LRH: Laparoscopic right hepatectomy; ORH: Open right hepatectomy; LLLS: Laparoscopic left lateral sectionectomy; OLLS: Open left lateral sectionectomy; HDU: High dependency unit; PACU: Post anesthesia care unit; LLR: Laparoscopic hepatic resection; OLR: Open liver resection.
Table 4 Hospital and operative costs of laparoscopic pancreatic resection vs open pancreatic resection
Ref. (n)Ward stayHDU/PACUEquipmentTheatreTotal costs
Kim et al[33] (128)
LPR (93)----4745 ± 1481
OPR (35)----4953 ± 3437
Eom et al[34] (31)
LPR (18)----4884 ± 1845
OPR (13)---3401 ± 1247
Waters et al[35] (60) 1
LPR (32)9828--307212900
OPR (28)12011--351015521
Fox et al[36] (118) 1
LPR (42)3404--465510842
OPR (76)5462--451013656
Abu Hilal et al[37] (51) 1
LPR (35)7446--988917337
OPR (16)25441--949834937
Limongelli et al[38] (45)
LPR (16)7894 ± 1771-2496 ± 1273469 ± 12611531 ± 1918
OPR (29)10540 ± 3230-1630 ± 3292388 ± 36113141 ± 3631
Overall (495)
LPR (249)6755-249655638825
OPR (246)9826-1630444413380
1Values are median (range). Values are mean ± SD unless indicated otherwise. HDU: High dependency unit; PACU: Post anesthesia care unit; LPR: Laparoscopic pancreatic resection; OPR: Open pancreatic resection.