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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 14, 2014; 20(42): 15549-15563
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15549
Table 1 Types of microbubbles used in contrast-enhanced harmonic endoscopic ultrasound
MicrobubbleCompanyShellGasSize (μm)StoragePreparationApproval
DefinityBristol-Myers Squibb Medical imaging Inc (New York)LipidsOctofluoropropane1.1-3.3Refrigerate 2 °C-8 °CActivate through Vialmix agitationWorldwide
SonovueBracco Diagnostics (Princeton, NJ)LipidsSulfurhexafluoride2-3No special storage conditionsReconstitute with 5 mL salineEurope, China, South Korea, Hong Kong, India, Singapore
SonazoidGE Healthcare (Piscataway, NJ)LipidsPerfluorobutane1-2-Reconstitute with 2 mL waterJapan