Effect of gastrectomy with bursectomy on prognosis of gastric cancer: A meta-analysis

Table 1 Major features of the included studies

Ref.	Year	Nation	Study type	Study year	TNM stage	Sample size		Outcomes	Quality score1
						Bursectomy(+)	Bursectomy(-)
Kochi et al[7]	2014	Japan	NRCT	2004-2009	pIA-IIIC	121	133	OS, RFS	15/24
Hasegawa et al[8]	2013	Japan	NRCT	2000-2009	pI-III	98	98	OS, RFS	17/24
Eom et al[9]	2013	South Korea	NRCT	2001-2006	cI-IV	107	363	OS, RFS	13/24
Fujita et al[10]	2012	Japan	RCT	2002-2007	cT2-T3	104	106	OS, RFS	3/5
Imamura et al[11]	2011	Japan	RCT	2002-2007	cT2-T3	104	106	-	3/5

¹Jadad score for RCTs, MINORS score for NRCTs. Fujita’s and Imamura’s reports were published by the same institute, were included as one study and share the same study number (the separately published data was complementary). NRCT: Non-randomized comparative studies; OS: Overall survival; RFS: Recurrence-free survival.

Table 2 Results of meta-analysis of the other four secondary outcomes

Outcomes	Subgroup	n	Heterogeneity		Effect size	95%CI of effect	P value
			I2	P value
Complications	NRCT	3	0.0%	0.794	RR = 0.98	0.78-1.22	0.838
	RCT	1	-	-	RR = 1.02	0.53-1.98	0.955
	Overall	4	0.0%	0.926	RR = 0.98	0.80-1.21	0.866
Operative time (min)	NRCT	3	79.6%	0.007	WMD = 57.18	35.57-78.79	0.000
	RCT	1	-	-	WMD = 244.20	230.38-258.02	0.000
	Overall	4	99.4%	0.000	WMD = 105.61	2.27-208.94	0.045
Blood loss (mL)	NRCT	2	78.9%	0.029	WMD = 229.63	106.77-352.49	0.000
	RCT	1	-	-	WMD = 338.00	184.21-491.79	0.000
	Overall	3	68.2%	0.043	WMD = 254.91	154.21-355.62	0.000
Hospital day (d)	NRCT	2	96.3%	0.000	WMD = 4.83	-12.96- 3.30	0.244
	RCT	0	-	-	-	-	-
	Overall	2	96.3%	0.000	WMD = -4.83	-12.96-3.30	0.244

NRCT: Non-randomized comparative study; RR: Relative risk; WMD: Weighted mean difference.