Laparoscopic liver resection: Wedge resections to living donor hepatectomy, are we heading in the right direction?

Table 1 Comparison of mortality, morbidity and conversion rates in some of the larger laparoscopic liver resection publications

Ref.	Year	Cases (n)	Malignant lesions (%)	Major hepatectomies (%)	Mortality (%)	Morbidity (%)	Conversion (%)
Descottes et al[92]	2003	87	0	3 (3.4)	-	4 (4.6)	9 (10)
Mala et al[93]	2005	53	89	-	-	8 (16)	3 (5.6)
Kaneko et al[51]	2005	52	NR	NR	-	5 (10)	1 (2)
Vibert et al[27]	2006	89	73	38 (43)	1 (1.1)	31 (34.8)	12 (13)
Cai et al[94]	2006	62	32	2 (3.2)	-	2 (3.2)	2 (3.2)
Koffron et al[16]	2007	273	37	96 (35)	-	NR	-
Chen et al[95]	2008	116	100	4 (3.4)	-	7 (6)	6 (5.2)
Buell et al[4]	2008	253	42	62 (42.5)	4 (1.6)	41 (16)	6 (2.4)
Bryant et al[32]	2009	166	60	31 (18.7)	-	25 (15.1)	16 (9.6)
Dagher et al[23]	2009	22	22	22	0	14	9
Yoon et al[39]	2010	69	-	21 (20)	-	5	5
Martin et al[25]	2010	90	90	90	0	23	4
Abu Hilal et al[24]	2011	36	-	36	0	14	11

Table 2 Some of the major laparoscopic liver resection for colorectal cancer series

Ref.	Year	n	Operative time(min)	Mortality	Blood loss (mL)	Conversion (%)	Hospital stay(d)
Rau et al[96]	1998	17	183	0	457	6	7.8
Shimada et al[97]	2001	17	325	0	400	0	12
Mala et al[98]	2002	13	187	0	600	0	4
Kaneko et al[51]	2005	30	182	0	350	3	14.9

Table 3 Some of the major laparoscopic liver resection for hepatocellular cancer series

Ref.	Year	PTS (n)	Cirrhosis present (%)	Tumor size (cm)	Morbidity(%)	Mortality(%)	OS(1 yr/5 yr, %)	RFS(1 yr/5 yr, %)
Dagher et al[36]	2010	163	73.6	3.6	22	1.2	92.6/64.9	77.5/32.2
Aldrighetti et al[99]	2010	16	56.2	4 + 2.2	25	0	-	-
Nitta et al[100]	2010	15	80	4.5	11.6	0	-	-
Yoon et al[39]	2010	69	55	3.1	21.7	0	90.4 (3 yr)	60.4 (3 yr)
Cherqui et al[101]	2009	37	74	-	34	0	-/72	-/44
Bryant et al[32]	2009	64	28	3.5	15.1	0	70 (3 yr)/65 (5 yr)	46 (3 yr)/34 (5 yr)
Chen et al[95]	2008	116	100	2.1	6	0	90/61	-
Buell et al[4]	2008	36	56	4.6	16	1.6	90/80	23 (2 yr)
Kaneko et al[51]	2005	30	100	3	10	0	97/61	87/31
Teramoto et al[102]	2005	11	67	2	26	0	100/80	75/40

OS: Overall survival; RFS: Recurrence-free survival.

Table 4 Some of the larger laparoscopic donor hepatectomy series wherein operative time, transfusion, blood loss, and hospital stay are discussed

Ref.	Method	n	Operative time (min)	Blood Loss (mL)	Transfusion	Conversion	Donor Morbidity	Hospital stay (d)
Soubrane et al[69]	Pure laparoscopy LLS	16	320 ± 67 vs 244 ± 55	18.7 ± 44.2 vs 199.2 ± 185.4	NIL	1/16	18.7% vs 35.7% (NS)	7.5 ± 2.3 vs 8.1 ± 3.0 (NS)
Kim et al[70]	Pure laparoscopy LLS	11	330 ± 68 vs 306 ± 29	396 ± 72 vs 464 ± 78	NIL	-	0/11 vs 1/11	6.9 ± 0.3 vs 9.8 ± 0.9
Koffron et al[16]	Lap assisted Right hepatectomy	20	-	-	-	-	-	-
Wakabayashi et al[83]	Lap assisted Right hepatectomy	7	-	-	-	-	-
Baker et al[78]	Lap assisted Right hepatectomy	33	265 ± 48 vs 316 ± 61`	417 ± 217 vs 550 ± 305	-	-	21.3% vs 21.3%	4.3 vs 3.9
Eguchi et al[79]	Hybrid Lap Assisted (Both Lobes)	15 (6-RL, 9-LL)	456	NA	NA	-	6.60%	-
Marubashi et al[89]	Hybrid Lap Assisted (Left lobe)	31 (LLS-17, LL-14)	510 ± 90	353 ± 396	-	NIL	6.70%	10.3 ± 3.3
Choi et al[91]	Lap Assisted and Single Port Lap Assisted	60 20( LADH) 40( SPLADH)	278 ± 72.25(SPLADH) 383.55 ± 41.73(LADH)	450 ± 316.43 (SPLADH) 873 ± 653.01 (LADH)	0.25 ± 0.81 (SPLADH) 1.25 ± 2.05 (LADH)	4/60	12/60	-