Bilici A. Prognostic factors related with survival in patients with pancreatic adenocarcinoma. World J Gastroenterol 2014; 20(31): 10802-10812 [PMID: 25152583 DOI: 10.3748/wjg.v20.i31.10802]
Corresponding Author of This Article
Ahmet Bilici, MD, Department of Medical Oncology, Medical Faculty, Istanbul Medipol University, TEM Avrupa Otoyolu Goztepe Cikisi No: 1, 34214 Bagcilar, Istanbul, Turkey. ahmetknower@yahoo.com
Research Domain of This Article
Oncology
Article-Type of This Article
Topic Highlight
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mOS in patients with a preoperative PLR of 150 or less was 19.7 mo, 13.7 mo in those with a PLR of 151-300, and 5.8 mo in patients with a value of > 300
Strong stromal SPARC expression was associated with worse DFS and OS (strong vs not-strong DFS 9.0 vs 12.6 mo, P = 0.005; OS 19.8 vs 26.6 mo (P = 0.033).Cytoplasmic SPARC expression was also associated with worse patient outcome (positive vs negative DFS 7.4 vs 12.1 mo, P = 0.041; OS 14.1 vs 25.6 mo, P = 0.011) in patients with pancreatic cancer who received gemcitabine as adjuvant CT
mOS for patients with a higher NEDD9 expression was significantly shorter than that of patients with lower NEDD9 expression. NEDD9 was an independent factor of poor prognosis
A higher FoxM1 expression had a significantly shorter survival time compared to patients with lower FoxM1 expression and FoxM1 was found to be an independent factor for survival
Citation: Bilici A. Prognostic factors related with survival in patients with pancreatic adenocarcinoma. World J Gastroenterol 2014; 20(31): 10802-10812