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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 21, 2014; 20(31): 10691-10702
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10691
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10691
Table 1 Series of orthotopic liver transplantation with liver grafts > 60 or > 65 years old
| Ref. | Cases > 60 or > 65 yr (n) | Donor mean age (yr) | Cold ischemic time (h) | Recipient mean age (yr) | Primary non-function | Patient survival (yr) | Graft survival (yr) |
| Marino et al[12] | 54 > 60 | 65.2 | 12.8 | 53.8 | 2-yr: 62% | 2-yr: 43% | |
| Washburn et al[106] | 29 > 60 | 63.7 | 10.6 | 6.7% | 1-yr: 58.6% | 1-yr: 44.8% | |
| Grande et al[107] | 40 > 60 | 68 | 6.5 | 5% | 1-yr: 82% | 1-yr: 77% | |
| 5-yr: 75% | 5-yr: 66% | ||||||
| Rodríguez et al[22] | 100 > 60 | 69 | 4.1 | 54 | 1% | 1-yr: 82% | 1-yr: 77.8% |
| 5-yr: 74.5% | 5-yr: 71.4% | ||||||
| Neipp et al[111] | 67 > 60 | 65 | 10.3 | 49 | 12% | 1-yr: 79% | 1-yr: 68% |
| 5-yr: 62% | 5-yr: 53% | ||||||
| Moore et al[20] | 35 > 60 | 5-yr: 48% | 5-yr: 35% | ||||
| Anderson et al[15] | 91 > 60 | 54 | 3.3% | 1-yr: 86.8% | 1-yr: 82.4% | ||
| 5-yr: 67.6% | 5-yr: 62.5% | ||||||
| Rauchfuss et al[110] | 54 > 65 | 8.4 | 1-yr: 70% | 1-yr: 70% | |||
| Martins et al[81] | 50 > 65 | 73.9 | 7.3 | 57.6 | 4% | 1-yr: 78% | |
| Jiménez-Romero et al[55] | 125 > 60 | 69.1 | 6.1 | 51.2 | 0.8% | 1-yr: 80.7% | 1-yr: 78.2% |
| 5-yr: 68.5% | 5-yr: 65.1% |
Table 2 Series of orthotopic liver transplantation with liver grafts older than 70 years
| Ref. | Cases (n) | Donor mean age (yr) | Cold ischemic time (h) | Recipient mean age (yr) | Primarynon-function | Patient survival (yr) | Graft survival(yr) |
| Emre et al[13] | 36 | 73.5 | 9 | 55 | 5.5% | 1-yr: 91% | 1-yr: 85% |
| Kim et al[54] | 25 | 74 | 7.6 | 49 | 8% | 1-yr: 95.4% | 1-yr: 82.7% |
| 3-yr: 89.8% | 3-yr: 71.7% | ||||||
| Gastaca et al[23] | 55 | - | 5 | - | 0% | 1-yr: 93.8% | 1-yr: 92.6% |
| 3-yr: 90.6% | 3-yr: 89.4% | ||||||
| Borchert et al[99] | 41 | 73.4 | 8.9 | 50.9 | 2.4% | 1-yr: 91% | 1-yr: 86% |
| 3-yr: 83% | 3-yr: 81% | ||||||
| 5-yr: 77% | 5-yr: 75% | ||||||
| Segev et al[25] (UNOS) | 1043 | 74.8 | 3-yr: 81.2% | 3-yr: 74.9% | |||
| Cescon et al[26] | 111 | - | 7% | 5-yr: 66% | 5-yr: 62% | ||
| Fouzas et al[65] | 17 | 73 | 7.2 | 57 | 11.8% | 1-yr: 69.7% | |
| 3-yr: 57.5% | |||||||
| 5-yr: 46.2% | |||||||
| Lai et al[61] | 28 | 74 | 6.4 | 57 | 3.6% | 5-yr: 47% | 5-yr: 40.7% |
| Sampedro et al[112] | 24 | 78.3 | 3.7 | 53.9 | 0% | 1-yr: 78% | |
| 5-yr: 63% | |||||||
| Darius et al[58] | 58 | 77 | 8 | 61 | 0% | 1-yr: 90% | 1-yr: 88% |
| 5-yr: 84% | 5-yr: 79% | ||||||
| Jiménez-Romero et al[55] | 50 | 75.7 | 6.1 | 51 | 0% | 1-yr: 76% | 1-yr: 73.9% |
| 5-yr: 62.9% | 3-yr: 64.6% | ||||||
| 5-yr: 58.3% |
Table 3 Series of orthotopic liver transplantation with liver grafts older than 80 years
| Ref. | Cases (n) | Donor mean age (yr) | Cold ischemic time (h) | Recipient mean age (yr) | Primary non-function | Patient survival (yr) | Graft survival(yr) |
| Jiménez-Romero et al[55] | 4 | 85.7 | 5.5 | 50.2 | 0% | 1-yr: 75% | 1-yr: 75% |
| Nardo et al[53] | 30 | 82.3 | 7.5 | 52.5 | 0% | 1-yr: 80% | 1-yr: 77% |
| Zapletal et al[24] | 5 | 9.5 | 52 | 0% | 1-yr: 100% | 1-yr: 100% | |
| Cescon et al[26] | 41 | 52.5 | 0% | 3-yr: 86% | 3-yr: 81% | ||
| 5-yr: 86% | 5-yr: 81% | ||||||
| Petridis et al[79] | 10 | 83.5 | 5 | 57.4 | 10% | 1-yr: 80% | |
| 3-yr: 40% | |||||||
| Singhal et al[80] (UNOS) | 197 | 58.5 | 1-yr: 81% | 1-yr: 75.5% | |||
| 3-yr: 69.1% | 3-yr: 61.2% |
- Citation: Jiménez-Romero C, Caso Maestro O, Cambra Molero F, Justo Alonso I, Alegre Torrado C, Manrique Municio A, Calvo Pulido J, Loinaz Segurola C, Moreno González E. Using old liver grafts for liver transplantation: Where are the limits? World J Gastroenterol 2014; 20(31): 10691-10702
- URL: https://www.wjgnet.com/1007-9327/full/v20/i31/10691.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i31.10691