Liver fibrosis evaluation by ARFI and APRI in chronic hepatitis C

Table 1 Comparison of acoustic radiation force impulse and AST/PLT ratio Index in different stages of liver fibrosis

Stages of liver fibrosis	Cases number	ARFI (m/s)	APRI
S1	41	1.23 ± 0.34	0.31 ± 0.45
S2	40	1.48 ± 0.43	0.28 ± 0.38
S3	30	2.06 ± 0.45ac	0.58 ± 0.59ac
S4	17	2.30 ± 0.87ac	0.65 ± 0.34ac
F value		1.536	1.268
P value		0.026	0.038

^aP < 0.05 vs S1;

^cP < 0.05 vs S2. ARFI: Acoustic radiation force impulse; APRI: AST/PLT ratio index.

Table 2 Comparison of the diagnostic significance of acoustic radiation force impulse detection and AST/PLT Ratio Index in different stages of liver fibrosis

Diagnostic parameters	≥S2		≥S3		S4
	ARFI	APRI	ARFI	APRI	ARFI	APRI
Diagnostic threshold	1.530	0.171	1.790	0.278	1.789	0.443
Area under curve	0.775	0.721	0.901	0.787	0.792	0.780
95%CI	0.692-0.867	0.620-0.837	0.786-0.954	0.721-0.886	0.664-0.933	0.678-0.876
Sensitivity	0.576	0.876	0.764	0.703	0.789	0.789
Specificity	0.895	0.564	0.965	0.765	0.754	0.812

ARFI: Acoustic radiation force impulse; APRI: AST/PLT ratio index.