Birthplace is not a determinant of colorectal adenomas

Table 1 Clinical characteristics according to birthplace

Characteristics	Australia/New Zealand	Asia	Europe	Middle East/Africa	South America	Pacific Islands	P-value
Age > 50 yr	56%	70%	85%	65%	74%	67%	< 0.01
Aspirin	17%	12%	17%	12%	9%	14%	0.16
NSAID	8%	5%	11%	10%	13%	0%	0.15
Smoking	2%	12%	21%	19%	26%	18%	0.09
Hypercholesterolemia	18%	25%	35%	25%	30%	20%	0.03
Diabetes	18%	19%	23%	21%	15%	60%	0.05

NSAID: Non-steroidal anti-inflammatory drugs.

Table 2 Adenoma detection rate according to birthplace

Birthplace	Adenoma detection rate1	P-value3	Advanced adenoma detection rate2	P-value3
Australia and New Zealand	47.50%		18.80%
Asia	29.50%	0.002	9.50%	0.03
Europe	50.40%	0.12	14.20%	0.25
Middle East and Africa	38.00%	0.50	9.90%	0.07
South America	40.70%	< 0.001	7.40%	0.04
Pacific Islands	31.80%	0.03	9.10%	0.25

¹Adenoma detection rate is defined as number of colonoscopies where one or more adenomas were detected divided by the total number of colonoscopies;

²Advanced adenoma detection rate is defined as number of colonoscopies where one or more advanced adenomas were detected divided by the total number of colonoscopies;

³χ² test between Australia and New Zealand-born and those born elsewhere.

Table 3 Predictors of polyp detection, adenoma detection, advanced adenoma detection

Univariate analysis	OR	95%CI	P-value	Multivariate analysis	OR	95%CI	P-value
Polyp detection
Male sex	2.5	1.8-3.5	< 0.001	Male sex	2.4	1.5-41	0.001
Older age	1.004	1.02-1.05	< 0.001	Older age	1.04	1.02-1.0	< 0.001
Aspirin use	0.5	0.4-0.9	0.008	Positive FOBT	0.2	0.1-0.5	0.003
Hypercholesterolemia	0.6	0.4-0.96	0.031
Diabetes	0.6	0.4-0.9	0.02
Anaemia	1.7	1.1-2.7	0.03
Positive FOBT	0.3	0.2-0.5	< 0.001
BMI	1.05	1.01-1.09	0.02
Smoking	0.65	0.43-0.96	0.03
Birthplace	-0.64	-0.43-0.01	0.12
Adenoma detection
Male sex	2.3	1.4-3.8	0.001	Male sex	2.0	1.2-3.4	0.01
Older age	1.02	1.01-1.04	0.01	Older age	1.02	1.003-1.04	0.03
NSAID use	3.4	1.2-9.5	0.02	Positive FOBT	0.2	0.1-0.6	0.002
Positive FOBT	0.2	0.1-0.5	0.001
Birthplace	0.02	-0.37-0.04	0.94
Advanced adenoma detection
Male sex	2.7	1.5-4.8	0.001	Male sex	2.3	1.2-4.2	0.008
Older age	1.04	1.02-1.06	< 0.001	Rectal bleeding	0.4	0.2-0.7	0.002
Rectal bleeding	0.5	0.3-0.8	0.008	Positive FOBT	0.1	0.1-0.3	< 0.001
Positive FOBT	0.2	0.1-0.4	< 0.001
Birthplace	-0.01	-0.03-0.01	0.21

FOBT: Faecal occult blood test; BMI: Body mass index.