Evolution of laparoscopy in colorectal surgery: An evidence-based review

Table 1 Summary of key papers on laparoscopic resection for colorectal cancer

Trial	Year of publication	Type of study	Numbers of patients	Key findings
Barcelona trial[14] Lap-assisted vs open colectomy	2002	RCT Single centre	219	Improved perioperative outcomes and hospital stay in lap group Survival benefit in stage III disease for lap group
COST study[15] Lap vs open colectomy	2004	RCT Multicentre	872	Longer operating time but quicker recovery for lap No difference in morbidity, mortality, recurrence or survival
COLOR trial[16] Lap vs open colectomy	2009	RCT Multicentre	1248	Supported findings of COST
CLASICC trial[17,19] Lap vs open colon and rectal cancers	2005 2010 (5 yr follow-up)	RCT Multicentre	794 (2:1 lap:open)	Equivalent perioperative and oncological outcomes 29% conversion rate Higher CRM involvement for rectal cancers with lap
Abraham et al[48] Short-term outcomes of lap vs open	2004	Meta-analysis of RCTs	2521 12 RCTs	Longer operative times, less morbidity and quicker recovery for lap Mortality and oncological outcomes equivalent
Cochrane review[18] Short-term outcomes after lap	2005	Systematic review		Less morbidity and quicker recovery for lap
Cochrane review[20] Long-term results after lap	2008	Systematic review		Equivalent oncological outcomes for lap vs open

RCT: Randomized controlled trial.