Helicobacter pylori isolates from ethnic minority patients in Guangxi: Resistance rates, mechanisms, and genotype

Table 1 Clinical characteristics of 26 patients from whom clarithromycin-resistant Helicobacter pylori strains were isolated

No.	Strain	Gender	Age	Ethnicity	Region	Disease type	History of medication	Family history of gastric disease	Antibiotic resistance
1	GXHP039	F	46	H	LY	PU	+	-	CA
2	GXHP051	F	46	H	BS	PU	+	+	CA
3	GXHP071	F	39	Ch	TY	CG	-	-	C
4	GXHP080	F	54	Ch	BS	CG	+	-	CAS
5	GXHP043	F	47	H	BS	PU	+	-	CA
6	GXHP093	M	46	Ch	TL	CG	-	-	CASG
7	GXHP004	F	49	Ch	TY	PU	-	-	C
8	GXHP014	F	46	Ch	BS	PU	+	-	CAS
9	GXHP016	F	57	Ch	BS	PU	-	+	CASG
10	GXHP019	M	52	Ch	LY	PU	-	+	C
11	GXHP021	M	51	Ch	TL	PU	+	-	CASG
12	GXHP023	M	48	Ch	LY	PU	+	-	CAG
13	GXHP026	M	41	Ch	TY	PU	-	-	C
14	GXHP121	M	46	H	TY	CG	+	-	C
15	GXHP085	M	53	Ch	TY	CG	-	+	C
16	GXHP034	M	51	Ch	BS	PU	-	-	CAG
17	GXHP090	M	41	Ch	BS	CG	-	-	C
18	GXHP067	M	41	H	BS	PU	+	-	C
19	GXHP056	M	39	H	TY	PU	-	+	CA
20	GXHP100	F	47	H	LY	CG	-	-	CA
21	GXHP104	F	46	H	TY	CG	+	-	CG
22	GXHP107	F	56	H	BS	CG	-	+	CAS
23	GXHP110	F	59	H	BS	CG	+	+	CAG
24	GXHP113	M	46	H	TL	CG	-	+	C
25	GXHP115	M	53	H	LY	CG	-	+	CAG
26	GXHP120	M	46	H	BS	CG	+	+	C

PU: Peptic ulcer; CG: Gastritis; Ch: Chuang; H: Han; M: Male; F: Female; BS: Baise; TY: Tianyang; LY: Lingyu; TL: Tianlin; +: A clear history; -: An unclear history; C: Clarithromycin; G: Gentamycin; S: Streptomycin; A: Amoxicillin.

Table 2 Clinical characteristics of 26 patients from whom clarithromycin-sensitive Helicobacter pylori strains were isolated

No.	Strain	Gender	Age	Ethnicity	Region	Disease type	History of medication	Family history of gastric disease
1	GXHP069	M	46	Ch	TL	CG	+	+
2	GXHP070	M	43	Ch	LY	CG	+	+
3	GXHP096	F	36	Ch	BS	CG	-	+
4	GXHP119	F	48	H	TY	CG	-	-
5	GXHP094	F	46	Ch	BS	CG	+	+
6	GXHP074	M	47	Ch	TL	CG	+	-
7	GXHP116	F	46	H	BS	CG	-	+
8	GXHP075	M	45	Ch	LY	CG	-	-
9	GXHP076	M	48	Ch	TY	CG	-	+
10	GXHP079	M	53	Ch	TL	CG	+	+
11	GXHP078	M	52	Ch	BS	CG	+	+
12	GXHP101	M	42	H	BS	CG	-	+
13	GXHP102	M	56	H	BS	CG	+	-
14	GXHP005	M	35	Ch	BS	PU	-	+
15	GXHP006	M	41	Ch	TL	PU	-	+
16	GXHP007	M	60	Ch	TL	PU	+	+
17	GXHP008	M	38	Ch	BS	PU	-	-
18	GXHP024	F	50	Ch	TL	PU	+	+
19	GXHP025	F	39	Ch	BS	PU	-	-
20	GXHP027	F	59	Ch	BS	PU	-	-
21	GXHP040	M	51	H	BS	PU	+	+
22	GXHP041	M	52	H	BS	PU	+	+
23	GXHP052	F	53	H	BS	PU	-	-
24	GXHP053	F	47	H	BS	PU	+	+
25	GXHP054	F	49	H	BS	PU	-	-
26	GXHP050	M	72	H	LY	PU	-	+

PU: Peptic ulcer; CG: Gastritis; Ch: Chuang; H: Han; M: Male; F: Female; BS: Baise; TY: Tianyang; LY: Lingyu; TL: Tianlin; +: A clear history; -: An unclear history.

Table 3 Frequencies of the presence of factors influencing genotype distribution of clarithromycin-resistant strains

	CG	PU	Ch	H	M	F	TY	TL	LY	BS	HMR	HM	FHGD	30-40 yr	41-50 yr	51-60 yr
Group I	0	2	0	2	2	0	0	0	1	1	2	2	0	0	2	0
Group II	0	11	8	3	4	7	3	1	2	5	4	5	4	1	6	4
Group III	1	0	0	1	1	0	0	0	1	0	1	1	1	0	1	0
Group IV	8	0	2	6	5	3	2	1	1	4	4	4	5	1	3	4
Group V	3	0	2	1	0	3	2	0	0	1	1	1	1	0	2	1
Group VI	1	0	1	0	0	1	0	1	0	0	1	0	0	0	1	0

CG: Gastritis; PU: Peptic ulcer; Ch: Chuang; H: Han; M: Male; F: Female; TY: Tianyang; TL: Tianlin; LY: Lingyu; BS: Baise; HMR: History of multidrug resistance; HM: History of medication; FHGD: Family history of gastric disease.

Table 4 Frequencies of the presence of factors influencing genotype distribution of clarithromycin-sensitive strains

	CG	PU	Ch	H	M	F	TY	TL	LY	BS	HM	FHGD	30-40 yr	41-50 yr	51-60 yr
Group I	9	0	7	2	0	9	1	2	2	4	2	6	0	6	3
Group II	4	0	2	2	4	0	1	0	0	3	1	3	1	3	0
Group III	0	11	5	6	4	7	1	2	1	7	3	7	3	3	5
Group IV	0	2	1	1	2	0	1	0	0	1	0	0	1	1	0

CG: Gastritis; PU: Peptic ulcer; Ch: Chuang; H: Han; M: Male; F: Female; TY: Tianyang; TL: Tianlin; LY: Lingyu; BS: Baise; HM: History of medication; FHGD: Family history of gastric disease.