Efficacy and tolerability of low-dose interferon-α in hemodialysis patients with chronic hepatitis C virus infection

Table 1 Patient baseline characteristics

Case	Sex	Age (yr)	Weight (kg)	HD duration (yr)	Cirrhosis	Genotype	HCV RNA (IU/mL)
1	M	52	62	5	N	1b	4805000
2	F	28	40	10	N	1b	3150000
3	M	28	69	14	N	1b	15840
4	M	38	52	6	N	1b	3600000
5	F	38	54	16	N	1b	3786000
6	F	36	47	2	N	1b	167000
7	F	47	48	14	N	1b	663000
8	M	40	59	9	N	1b	356000
9	M	39	63	13	N	1b	156000
10	M	41	67	2	N	2a	15580
11	F	58	50	6	N	2a	9590
12	M	28	55	2	N	1b	209200
13	M	41	63	3	N	1b	39460
14	M	33	59	6	N	1b	143000
15	F	32	52	7	N	2a	446400
16	M	36	67	6	N	1b	456000
17	F	27	51	4	N	1b	14500
18	F	29	49	4	N	1b	12200
19	M	45	62	11	Y	1b	266000

HCV: Hepatitis C virus; HD: Hemodialysis; F: Female; M: Male.

Table 2 Patient treatment results

Case	IFN-αtype	HCV RNA (IU/mL)
		12 wk	48 wk	72 wk	96 wk	144 wk
1	PegIFNα-2a	405100	Positive	Positive	Positive	Positive
2	PegIFNα-2a	Negative	Negative	Negative
3	PegIFNα-2a	Negative	Negative	Negative	Negative	Negative
4	PegIFNα-2a	Negative	Negative	Negative	Negative	Negative
5	PegIFNα-2a	Negative	Negative	Negative	Negative
6	PegIFNα-2a	Negative	Negative	Negative	Negative
7	PegIFNα-2a	2380	Negative	Negative	Negative
8	PegIFNα-2a	Negative	Negative	Negative	Negative
9	PegIFNα-2a	Negative	Negative	Negative
10	PegIFNα-2a	Negative	Negative	Negative	Negative
11	PegIFNα-2a	Negative	Negative	Negative	Negative
12	PegIFNα-2a	Negative	Negative	Negative	Negative
13	IFNα-2b	Negative	Negative	Negative
14	IFNα-2b	Negative	Negative	Negative	Negative
15	IFNα-2b	Negative	Negative	Negative	Negative
16	IFNα-2b	256000	Positive	Positive
17	IFNα-2b	Negative	Negative	Negative
18	IFNα-2b	Negative	Negative	Negative
19	IFNα-2b	Negative	Positive	Positive

IFN: Interferon; PEG-IFN: Pegylated interferon; HCV: Hepatitis C virus.