Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett’s esophagus: A pilot ex-vivo study

Table 1 Diagnostic performance of endocytoscopy in Barrett’s esophagus

	Classification	Sensitivity	Specificity	PPV	NPV
Experienced physicians (staff physician)	BEC 1	1.000%	1.000%	1.000%	1.000%
	BEC 2	1.000%	0.944%	0.857%	1.000%
	BEC 3	0.833%	0.944%	0.833%	0.944%
	BEC 4	0.833%	1.000%	1.000%	0.947%
Inexperienced physicians (clinical fellow)	BEC 1	0.977%	1.000%	1.000%	0.992%
	BEC 2	0.636%	0.894%	0.667%	0.881%
	BEC 3	0.705%	0.871%	0.646%	0.898%
	BEC 4	0.955%	0.992%	0.977%	0.985%
Both experienced and inexperienced (physicians staff physician and clinical fellow)	BEC 1	0.980%	1.000%	1.000%	0.993%
	BEC 2	0.680%	0.900%	0.694%	0.894%
	BEC 3	0.720%	0.880%	0.667%	0.904%
	BEC 4	0.940%	0.993%	0.979%	0.980%

PPV: Positive predictive value; NPV: Negative predictive value.

Table 2 Interobserver agreement of endocytoscopy in Barrett’s esophagus

Classification	Staff physician (95%CI)	GI fellow (95%CI)
BEC 1-4	0.932 (0.794-0.985)	0.897 (0.784-0.973)
BEC 1 and 2 vs 3 and 4	0.851 (0.593-0.965)	0.581 (0.358-0.856)

GI: Gastrointestinal.