Interleukin 28B-related polymorphisms: A pathway for understanding hepatitis C virus infection?

Table 1 Demographic characteristics of the study participants

Characteristic	HCV (n = 145)	Control (n = 198)
Age (yr), mean ± SD	55.5 ± 10.0	32.2 ± 10.0
Sex, M/F	52%/48%	66%/34%
Skin color
White	75.70%	88.00%
Black	19.20%	5.00%
Brown	5.10%	7.00%

HCV: Hepatitis C virus.

Table 2 Demographic characteristics and clinical parameters of hepatitis c virus-infected patients stratified by response to treatment

Feature	SVR (n = 55)	NR (n = 89)	P value
Sex, M/F	54%/46%	51%/49%	0.072
Skin color
White	89%	70%	0.032
Black	11%	26%	0.009
Brown	-	4%	ND
ALT in UI/mL, mean (IQR)	97 (54)	77 (64)	0.1
Baseline viral load in UI/mL1
< 600000	47.80%	49.30%	0.760
≥ 600000	52.20%	50.70%	0.890
Fibrosis score2
0-2	63.30%	49.40%	0.125
3-4	36.70%	50.60%	0.126

¹This parameter was only available for 115 patients [46 of sustained virological response (SVR), and 69 of non-responders (NR)];

²According to histopathological analysis of liver biopsy tissues; this parameter was only available for 128 patients (49 of SVR, and 79 of NR). ND: Not done due to small numbers of cases; ALT: Alanine aminotransferase.