Brief Article
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 7, 2013; 19(37): 6207-6213
Published online Oct 7, 2013. doi: 10.3748/wjg.v19.i37.6207
Table 1 Subject demographics and disease characteristics n (%)
CountryGroupEthnicityGroup No.Age (yr) mean ± SDFemaleNever smokerFamily history of IBDCD (severe behaviour)CD (ileocolonic location)UC proctitis
Australia(n = 48)Crohn’sCaucasian929 ± 124 (44)3 (33)0 (0)8 (89)7 (78)-
UCCaucasian1037 ± 115 (50)7 (70)1 (10)--1 (10)
Asian1045 ± 142 (20)8 (80)0 (0)--3 (10)
HealthyCaucasian1046 ± 125 (50)4 (40)0 (0)---
Asian951 ± 114 (44)7 (78)1 (11)---
Hong Kong(n = 42)Crohn'sAsian1238 ± 157 (58)7 (58)1 (8)3 (25)9 (75)-
UCAsian1243 ± 125 (42)12 (100)0 (0)--2 (17)
HealthyAsian1050 ± 56 (60)7 (78)0 (0)---
RelativesAsian834 ± 93 (38)6 (75)8 (100)---
Total9042 ± 1341 (46)61 (68)11 (12)11 (52)16 (76)6 (19)
Table 2 Antibody positivity and titre according to geography, ethnicity and disease n (%)
Australia
Hong Kong (all Asian)
CD
UC
Healthy
CDUCHealthyRelatives
CaucasianCaucasianAsianCaucasianAsian
Total910101091212108
Antibody positivity
gASCA6 (67)ac0 (0)1 (10)1 (10)0 (0)0 (0)0 (0)0 (0)0 (0)
ALCA4 (44)a1 (10)0 (0)2 (20)0 (0)1 (8)1 (8)0 (0)0 (0)
ACCA2 (22)1 (10)0 (0)2 (20)3 (33)1 (8)1 (8)1 (10)0 (0)
AMCA6 (67)a0 (0)0 (0)1 (10)3 (33)7 (58)a2 (17)2 (20)2 (25)
pANCA0 (0)7 (70)e5 (50)e0 (0)1 (11)3 (25)4 (33)e0 (0)0 (0)
No. of positive antibodies
At least 19 (100)ac2 (20)1 (10)2 (20)4 (44)7 (58)a4 (33)2 (20)2 (25)
At least 26 (67)ac0 (0)0 (0)2 (20)2 (22)2 (17)0 (0)1 (10)0 (0)
Antibody/QSS titre median (range)
gASCA59 (146)ac10 (12)9 (47)17 (45)8 (21)9 (44)2 (39)11 (17)5 (46)
ALCA46 (79)a17 (86)14 (38)23 (77)18 (34)27 (69)a17 (82)17 (18)24 (25)
ACCA50 (188)39 (101)43 (56)60 (310)76 (135)50 (80)37 (87)46 (77)34 (62)
AMCA111 (154)a63 (47)70 (60)79 (59)75 (116)121 (459)a60 (272)59 (145)74 (94)
QSS14 (5)a9 (6)10 (6)12 (8)9 (10)13 (10)a8 (7)8 (10)10 (9)