Heme oxygenase-1 and gut ischemia/reperfusion injury: A short review

Table 1 The role of heme oxygenase-1 for the protection of intestinal ischemia/reperfusion injury

	Treatment	I/R model	Ref.
HO-1
	Glutamine	Warm ischemia	[30]
	Ischemic preconditioning	Resuscitation after shock	[37]
	Doxorubicin	Warm ischemia	[20]
	Hypothermia	Warm ischemia	[32]
	IL-2	Warm ischemia	[34]
	Hemin	Warm ischemia	[29]
	Hypertonic saline	Warm ischemia	[31]
	Pyrrolidine dithiocarbamate	Warm ischemia	[28]
	Hyperthermia	Warm ischemia	[33]
	Ischemic preconditioning	Warm ischemia	[36]
	Cobalt-protoporphyrin	Warm ischemia	[27]
	Ischemic preconditioning	Endotoxic shock	[18]
	Radix Paeoniae Rubra	Warm ischemia	[38]
	AICAR preconditioning	Warm ischemia	[35]
CO
	Gas inhalation	Intestinal transplants	[11]
	Gas inhalation	Intestinal transplants	[13]
	Gas inhalation	Intestinal transplants	[14]
	Gas inhalation	Intestinal transplants	[47]
	CO solution	Intestinal transplants	[49]
	CORM preconditioning	Warm ischemia	[48]
	CORM preconditioning	Warm ischemia	[12]
Biliverdin/bilirubin
	Bilirubin	Warm ischemia	[60]
	Bilirubin	Warm ischemia	[61]
	Biliverdin	Intestinal transplants	[47]

AICAR: 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside; CORM: CO-releasing molecules; IL-2: Interleukin-2; I/R: Ischemia/reperfusion; HO: Heme oxygenase.