Electrogastrography associated with symptomatic changes after prokinetic drug treatment for functional dyspepsia

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Nov 7, 2012 (publication date) through Sep 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2012; 18(41): 5948-5956
Published online Nov 7, 2012. doi: 10.3748/wjg.v18.i41.5948

Table 1 Patient demographics and pattern of dysrhythmia according to symptom improvement

	Total patients (n = 74)		Symptom improvement (n = 52)		Symptom resistance (n = 22)
Male:female (n)	26:48		18:34		8:14
Age (range), yr	51.7 (19-70)		53.5 (27-70)		47.6 (19-70)
Height	165.2 ± 12.4		166.3 ± 11.6		164.9 ± 10.1
Weight	61.3 ± 9.7		62.3 ± 9.1		58.8 ± 10.2
	Pre-treatment	Post-treatment	Pre-treatment	Post-treatment	Pre-treatment	Post-treatment
Symptom severity score	8.09 ± 0.43	5.51 ± 0.46^a	8.90 ± 0.46	4.52 ± 0.47^a	6.18 ± 0.85	7.86 ± 0.92
Symptom frequency score	9.27 ± 0.49	6.81 ± 0.54^a	9.96 ± 0.54	5.79 ± 0.60^a	7.64 ± 1.01	9.23 ± 0.97
Gastric dysrhythmia (pre-prandial)
Bradygastria	16 (21.6)	11 (14.9)	9 (17.3)	7 (13.5)	6 (27.3)	4 (18.2)
Normogastria	33 (44.6)	52 (70.3)^a	26 (50.0)	37 (71.2)^a	9 (40.9)	15 (68.2)
Tachygastria	25 (33.8)	11 (14.9)^a	17 (32.7)	8 (15.4)^a	7 (31.8)	3 (13.6)
Gastric dysrhythmia (post-prandial)
Bradygastria	17 (23.0)	10 (13.5)	10 (19.2)	6 (11.5)	4 (18.2)	4 (18.2)
Normogastria	33 (44.6)	45 (60.8)	26 (50.0)	37 (71.2)^a	11 (50)	13 (59.1)
Tachygastria	24 (32.4)	19 (25.7)	16 (30.8)	14 (26.9)	7 (31.8)	5 (22.7)

^aP < 0.05 vs pre-treatment group. Data are presented by mean ± SD or n (%).

Table 2 Demographic and treatment success of patients and pattern of dysrhythmia according to prokinetic drugs

	Itopide (n = 24)		Mosapride (n = 28)		Levosulpiride (n = 22)
Male:female (n)	5:19		10:18		11:11
Age (range), yr	49.8 (30-64)		49.6 (19-70)		56.6 (39-70)
Height	166.1 ± 10.1		163.0 ± 11.0		167.1 ± 13.2
Weight	60.8 ± 7.7		62.7 ± 11.5		61.3 ± 10.5
Symptom improvement	18 (75)		17 (61)		17 (77)
	Pre-treatment	Post-treatment	Pre-treatment	Post-treatment	Pre-treatment	Post-treatment
Symptom severity score	7.96 ± 0.84	5.00 ± 0.86^a	7.61 ± 0.64	5.46 ± 0.79^a	8.86 ± 0.76	6.14 ± 0.76^a
Symptom frequency score	9.21 ± 0.92	6.08 ± 0.99^a	8.86 ± 0.78	6.86 ± 0.89	9.86 ± 0.83	7.55 ± 0.96
Gastric dysrhythmia (pre-prandial)
Bradygastri	5 (20.8)	4 (16.7)	6 (21.4)	4 (14.3)	4 (18.2)	3 (13.6)
Normogastria	8 (33.3)	17 (70.8)^a	15 (53.6)	18 (64.3)	12 (54.5)	15 (68.2)
Tachygastria	11 (45.8)	3 (12.6)^a	7 (25)	6 (21.4)	6 (27.3)	4 (18.2
Gastric dysrhythmia (post-prandial)
Bradygastria	5 (20.8)	3 (12.5)	6 (21.4)	6 (21.4)	3 (13.6)	1 (4.5)
Normogastria	11 (45.8)	14 (58.3)	12 (42.9)	16 (57.1)	14 (63.6)	15 (68.2)
Tachygastria	8 (33.3)	7 (29.2)	10 (35.7)	6 (21.4)	5 (22.7)	6 (27.3)

^aP < 0.05 vs pre-treatment group. Data are presented by mean ± SD or n (%).

Citation: Lim HC, Lee SI, Chen JD, Park H. Electrogastrography associated with symptomatic changes after prokinetic drug treatment for functional dyspepsia. World J Gastroenterol 2012; 18(41): 5948-5956
URL: https://www.wjgnet.com/1007-9327/full/v18/i41/5948.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i41.5948