Effects of octreotide on glucose transporter type 2 expression in obese rat small intestine

Table 1 Obesity and metabolic indicators in normal control and obese rats, and in obese rats treated with octreotide

	Control (n = 18)	Obese (n = 16)	Octreotide treated (n = 15)
Body weight (g)	378.54. ± 111.75	605.61 ± 141.00b	508.27 ± 94.39bc
Lee’s index	318.73 ± 20.10	337.61 ± 10.82b	334.67 ± 16.56a
Glucose (mmol/L)	7.33 ± 0.70	8.60 ± 1.38b	7.58 ± 1.51c
Sucrase activity (U/mg protein)	53.84 ± 17.98	48.90 ± 13.95	35.85 ± 21.31
Maltase activity(U/mg protein)	50.43 ± 30.49	156.01 ± 58.81b	112.85 ± 51.86a
Mucosa GLUT2 (IOD)	170546.5 ± 50646.14	390744.2 ± 62469.21b	269975.2 ± 53730.94bd
Apical GLUT2 (IOD)	354.98 ± 57.19	26740.18 ± 3809.60b	3758.06 ± 364.51ad
GLUT2 mRNA (IOD)	0.07 ± 0.02	0.26 ± 0.11b	0.08 ± 0.02bd
Western-blotting (IOD)	1.27 ± 0.38	2.08 ± 0.59b	1.31 ± 0.29d

^aP < 0.05,

^bP < 0.01 vs normal control group;

^cP < 0.05,

^dP < 0.01 vs obese group. GLUT2: Glucose transporter type 2; IOD: Integrated optical density.